钌(Ⅱ)催化C-H芳基化反应研究进展  

Recent Progress in Ru(Ⅱ)-Catalyzed C-H Arylation

作　　者：高杰 张殊佳[1] GAO Jie;ZHANG Shu-jia(Liaoning Key Laboratory of Bio-organic Chemistry,Dalian University,Dalian 116622,China)

机构地区：[1]大连大学辽宁省生物有机化学重点实验室,辽宁大连116622

出　　处：《大连大学学报》2018年第3期34-42,45,共10页Journal of Dalian University

摘　　要：官能化的含联芳基的化合物是有机化学领域中具有重要价值的合成骨架之一,在医药、功能材料和农用化学品领域具有广泛的应用价值。近年来,研究人员报道了许多官能团耐受性良好、低成本高效率和符合原子经济性的钌(Ⅱ)催化的C-H芳基化反应。这些方法为取代传统的C-H官能化和交叉偶联方法提供了强有力的替代方案。许多新的钌(Ⅱ)催化的C-H芳基化反应可以高效的合成其他方法无法得到的官能化的联芳基化合物,因此这些合成方法具有巨大的潜在应用价值。The functionalized biaryl-containing compound is one of the important synthetic frameworks in the field of organic chemistry and have a wide range of applications in medicine,functional materials,and agrochemicals.In recent years,many Ru(II)-catalyzed C-H arylation reactions with well-tolerated functional groups,low cost,high efficiency and atomic economy,have been reported.These methods provide a powerful alternative to replacing conventional C-H functionalization and cross-coupling methods.The functionalized biaryl compounds that are not obtainable by other methods can be efficiently synthesized in many new Ru(II)-catalyzed C-H arylation reactions,so these synthetic methods have enormous potential applications.

关 键 词：钌催化 芳基化 联芳基化合物 

分 类 号：O625.13[理学—有机化学]