支原体IgM抗体阳性肺炎患者的凝血、炎症指标的变化  

Changes of blood coagulation and inflammation index in patients with mycoplasma IgM antibody positive pneumonia

作　　者：于国云[1] 张庆[1] 杜丽艳[1] 曹立杰 YU Guoyun;ZHANG Qing;DU Liyan;CAO Lijie(Department of Respiratory,the Affiliated Hospital of Chengde Medical Univerisity,Chengde,Hebei 067000,China)

机构地区：[1]承德医学院附属医院呼吸内科,河北承德067000

出　　处：《重庆医学》2018年第20期2703-2705,共3页Chongqing medicine

摘　　要：目的探讨社区获得性肺炎(CAP)支原体IgM抗体阳性患者的凝血、降钙素原(PCT)、C反应蛋白(CRP)的变化及意义。方法收集该院2016年住院的肺炎患者,对其进行病原体抗体、血常规、PCT、CRP等指标检测,并按支原体IgM抗体阳性与否进行分组比较。结果支原体IgM抗体阳性组D二聚体(D-dimer)、纤维蛋白降解产物(FDP)较支原体IgM抗体阴性组、对照组偏高,凝酶原时间(PT)、活化的部分凝血活酶时间(APTT)较其他两组缩短,差异有统计学意义(P<0.05);支原体IgM抗体阳性组CRP较其他两组明显偏高,PCT较对照组偏高,较支原体IgM抗体阴性组差异无统计学意义(P<0.05)。结论社区获得性肺炎病原体IgM抗体阳性患者中以支原体IgM抗体阳性患者居多,阳性率为61.48%;支原体IgM抗体阳性的肺炎患者较支原体IgM抗体阴性患者及对照组D-dimer、FDP、CRP明显升高,PT、APTT明显降低。PCT在支原体IgM抗体阳性组较对照组有所升高。Objective To investigate the changes and significance of coagulation,procalcitonin(PCT)and C-reactive protein(CRP)in positive mycoplasma IgM antibody patients with community-acquired pneumonia(CAP).Methods The pneumonia patients who were in hospital in 2016 were collected and tested for pathogen antibodies,blood routines examination,PCT,CRP,and divided into groups according to whether mycoplasma IgM antibody was positive or not.Results The levels of D-dimer and fibrin degradation product(FDP)of the IgM positive group was higher than those of the IgM negative group and the control group,the levels of prothrombin time(PT)and activated partial thromboplastin time(APTT)in the IgM positive group were shorter than those of the other two groups(P<0.05).The level of CRP in the IgM positive group was higher than that of the other two groups;the level of PCT was higher than that of the control group,and there was no statistical difference between the IgM positive and negative group(P<0.05).Conclusion Among the CAP patients with positive IgM antibody,the majority of whom were the mycoplasma positive IgM antibody pneumonia patients,its positive rate is 61.48%.D-dimer,FDP and CRP increased,while PT and APTT decreased in the mycoplasma positive IgM antibody pneumonia patients.PCT was higher in the IgM positive group than that of the control group.

关 键 词：肺炎 支原体IgM抗体 凝血 炎症指标 

分 类 号：R563-1[医药卫生—呼吸系统]