布地奈德雾化吸入联合机械振动排痰治疗喘息性肺炎临床分析  

Inhalation of budesonide and mechanical vibration for asthmatic pneumonia

作　　者：傅光华 梁美嫦 谭清 余韶卫[2] Fu Guanghua;Liang Meichang;Tan Qing;Yu Shaowei(Department of Pediatrics,Luoding Maternal and Child Health Care Hospital,Yunfu 527200,China;Department of Pediatrics,Fourth Hospital,Medical College,Jinan University(Guangzhou Red Cross Hospital),Guangzhou 510613,China)

机构地区：[1]罗定市妇幼保健院儿科,527200 [2]暨南大学医学院第四附属医院广州市红十字会医院儿科,广州510613

出　　处：《国际医药卫生导报》2018年第14期2118-2121,共4页International Medicine and Health Guidance News

摘　　要：目的 观察评价布地奈德雾化吸入联合机械振动排痰(MV)治疗小儿喘息性肺炎(PAP)的临床效果。方法 选择2016年2月至2018年3月期间罗定市妇幼保健院儿科收治的小儿喘息性肺炎患者106例,并随机对照试验分为两组,各53例。对照组在常规治疗的基础上给予布地奈德雾化吸入治疗;观察组在对照组基础上给予机械振动排痰治疗,两组临床效果比较。结果 观察组总有效率为92.45%,显著高于对照组75.47%,差异有统计学意义(P<0.05);两组嗜酸粒细胞、嗜酸粒细胞阳离子蛋白水平较治疗前显著改善,且观察组优于对照组,差异有统计学意义(P<0.05);观察组咳嗽、湿啰音、喘鸣音消失时间及气急缓解时间均显著少于对照组,差异有统计学意义(P<0.05)。结论 布地奈德雾化吸入联合机械振动排痰(MV)治疗小儿喘息性肺炎(PAP)疗效确切,能够显著改善患儿炎症指标水平,缓解临床症状,有效提高临床效果,值得临床大力推广应用。Objective To observe and evaluate the clinical effect of inhalation of budesonide combined with mechanical vibration(MV)in the treatment of pediatric asthmatic pneumonia(PAP).Methods A total of 106 children with PAP admitted into Luoding Maternal and Child Health Care Hospital from February,2016 to March,2018 were selected,and were randomly divided into a control group and an observation group,53 cases for each group.The control group were routinely treated and inhaled budesonide;in addition,the observation group were treated with mechanical vibration and drainage.The clinical effects of the two groups were compared.Results The total effective rate was significantly higher in the observation group than in the control group(92.45%vs.75.47%,P<0.05).The levels of eosinophil and eosinophil cationic protein were better after than before the treatment in both groups and were better in the observation group than in the control group after the treatment(P<0.05).The times for the disappearance of cough,wet rales,and wheezing sound and the time for relieving shortness of breath were significantly shorter in the observation group than in the control group(P<0.05).Conclusion Inhalation of budesonide and mechanical vibration for asthmatic pneumonia is effective and can significantly improve the children’inflammation level and relieve clinical symptoms,so it is worth being clinically generalized.

关 键 词：小儿喘息性肺炎 布地奈德 机械振动排痰 

分 类 号：R725.6[医药卫生—儿科]