茴三硫胶囊联合胆益宁片治疗慢性胆囊炎的临床效果观察  

Clinical observation on chronic cholecystitis treated with anethol trithione capsules combined with Danyining tablets

作　　者：苏提 Su Ti(Department of Gastroenterology,Runan County Hospital of Traditional Chinese Medicine,Henan 463300,China)

机构地区：[1]汝南县中医院消化内科,河南463300

出　　处：《国际医药卫生导报》2018年第13期2029-2031,共3页International Medicine and Health Guidance News

摘　　要：目的 探讨茴三硫胶囊联合胆益宁片治疗慢性胆囊炎的临床效果。方法 收集本院2015年1月至2017年3月治疗的94例慢性胆囊炎患者,按照随机数表法分为两组,各47例。对照组给予胆益宁片治疗,观察组在对照组基础上联合茴三硫胶囊治疗。两组血浆TNF-α、β-EP、血清SOD、治疗效果及用药安全性比较。结果 治疗后,对照组血浆TNF-α、β-EP水平分别为(1.32±0.25)ng/ml、(16.37±2.85)mmol/L,均高于观察组的(1.17±0.23)ng/ml、(14.85±2.34)mmol/L,血清SOD水平为(610.67±85.74)ng/ml,低于观察组的(705.36±78.42)ng/ml,差异有统计学意义(t=3.027、2.826、5.587,P<0.05);对照组治疗总有效率为78.72%,低于观察组的93.62%,差异有统计学意义(χ2=4.374,P<0.05)。结论 茴三硫胶囊联合胆益宁片治疗慢性胆囊炎效果显著,可有效改善血浆TNF-α、β-EP及血清SOD水平,且用药安全可靠。Objective To investigate the clinical effect of anethol trithione capsules combined with Danyining tablets in the treatment of chronic cholecystitis.Methods 94 patients with chronic cholecystitis in our hospital from January 2015 to March 2017 were collected and were divided into the two groups with the random number table method,47 cases in each group.The control group was treated with Danyining tablets,and the observation group was treated with anethol trithione capsules on the basis of the control group.The levels of plasma TNF-α,plasmaβ-EP,and serum SOD,the therapeutic effect and medication safety in the two groups were compared.Results The plasma levels of TNF-αandβ-EP in the control group were(1.32±0.25)ng/ml and(16.37±2.85)mmol/L,respectively,which were significantly higher than those in the observation group[(1.17±0.23)ng/ml and(14.85±2.34)mmol/L],serum SOD level was(610.67±85.74)ng/ml,which was lower than that in the observation group[(705.36±78.42)ng/ml],with statistically significant differences(t=3.027,2.826,5.587;P<0.05).The total effective rate of the control group was 78.72%,which was lower than that of the observation group(93.62%),with statistically significant difference(χ2=4.374,P<0.05).Conclusion Anethol trithione capsules combined with Danyining tablets has significant effect in the treatment of chronic cholecystitis,which can effectively improve the levels of plasma TNF-α,plasmaβ-EP,and serum SOD,and is safe and reliable.

关 键 词：慢性胆囊炎 茴三硫胶囊 胆益宁片 血浆TNF-Α Β-EP 血清SOD 

分 类 号：R259[医药卫生—中西医结合]