壳聚糖负载氯化铜催化苯甲醛乙二醇缩醛  

Catalytic Synthesis of Benzaldehyde Glycol Acetal by Chitosan Doped with CuCl_2 as Catalysts

作　　者：顾海宁 吴政杰 丁雨茜 缪艳丽 彭杰 徐伟明[3] 韩晓祥[1] GU Haining;WU Zhengjie;DING Yuxi;MIAO Yanli;PENG Jie;XU Weiming;HAN Xiaoxiang(Department of Applied Chemistry,Zhejiang Gongshang University,Hangzhou 310018,China;Zhejiang Benli Technology Co.,Ltd,Taizhou 317016,China;College of Material,Chemistry and Chemical Engineering,Hangzhou Normal University,Hangzhou 310036,China)

机构地区：[1]浙江工商大学应用化学系,浙江杭州310018 [2]浙江本立科技股份有限公司,浙江台州317016 [3]杭州师范大学材料与化学化工学院,浙江杭州310036

出　　处：《杭州师范大学学报（自然科学版）》2018年第4期347-353,共7页Journal of Hangzhou Normal University(Natural Science Edition)

基　　金：杭州市农业与社会发展科研自主申报项目(20170533B02)

摘　　要：以壳聚糖和金属氯化物为原料制备了多种催化剂,并将其应用到苯甲醛乙二醇的缩醛反应.考察醇醛的物质的量比、反应时间、催化剂用量、带水剂的量等因素对反应的影响.实验结果表明,壳聚糖负载CuCl2作为催化剂时效果最好.通过响应面分析法得出该缩醛反应的最佳工艺条件为:n(醇)∶n(醛)=1.4∶1,催化剂用量为0.25g,反应时间3h,带水剂用量12.5mL,此条件下缩醛反应的产率90.0%,结果与模型预测值基本相符.Different catalysts were prepared with chitosan and metalchloride as the raw materials,and applied to the acetalization of benzaldehyde glycol acetal.The effects of various reaction conditions,including aldehyde/alcohol molar ratio,reaction time,amount of catalysts and amount of water carrying agent were investigated.It was shown that chitosan doped with CuCl2 had the best catalytic performance,and the optimal conditions for esterification catalyzed by chitosan doped with CuCl2 were as follows:n(glycol)∶n(benzaldehyde)=1.4∶1,the amount of catalyst was 0.25 g,the reaction time was 3 h and the amount of water-carrying agent was 12.5 mL.Under these conditions,the best yield of acetalization reaction reached 90.0%,in basic agreement with the values predicted by the mathematical model.

关 键 词：壳聚糖 响应面法 缩醛反应 

分 类 号：O625[理学—有机化学]