混合型生物人工肝治疗HBV相关慢加急性肝衰竭患者的临床疗效分析  

Clinical effect analysis of mixed bioartificial liver in the treatment of patients with HBV associated acute on chronic liver failure

作　　者：胡顺霖 李敏 叶江锋 张静 Hu Shunlin;Li Min;Ye Jiangfeng;Zhang Jing(Department of Gastroenterology,the First People's Hospital of Xiangyang City Affiliated to Hubei Medical College,Hubei Xiangyang 441000)

机构地区：[1]湖北医药学院附属襄阳市第一人民医院消化内科,441000

出　　处：《中国社区医师》2018年第22期24-25,共2页Chinese Community Doctors

摘　　要：目的:探讨混合型生物人工肝治疗HBV相关慢加急性肝功能衰竭(ACLF)患者的临床疗效。方法:收治HBV相关ACLF患者68例,依据治疗方式分为两组。对照组给予普通血浆置换治疗,研究组给予混合型生物人工肝治疗。比较两组临床疗效。结果:研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组ALB、ALT高于对照组,TBil低于对照组,差异有统计学意义(P<0.05)。结论:混合型生物人工肝治疗HBV相关ACLF患者的临床疗效显著。Objective:To explore the clinical effect of mixed bioartificial liver in the treatment of patients with HBV associated acute on chronic liver failure.Methods:68 cases of patients with HBV associated acute on chronic liver failure were divided into two groups according to the treatment.The control group was treated with general plasmapheresis,and the research group was treated with mixed bioartificial liver,the clinical effect of the two groups was compared.Results:The total effective rate of the research group was higher than that of the control group,the difference was statistically significant(P<0.05).After treatment,the ALB and ALT levels in the research group were higher than those in the control group,and the TBil index was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of mixed bioartificial liver in the treatment of patients with HBV related acute on chronic liver failure was more significant.

关 键 词：血浆置换 混合型生物人工肝 慢加急性肝功能衰竭 

分 类 号：R512.62[医药卫生—内科学] R575.3[医药卫生—临床医学]