腹膜透析治疗艾滋病毒感染并终末期肾病14例临床观察  

作　　者：刘建威[1] 张愚[1] 朱志强[1] 谢青南[1] 张萌萌 郑鑫[1] 

机构地区：[1]首都医科大学附属北京佑安医院,北京100069

出　　处：《中国药业》2017年第A02期143-145,共3页China Pharmaceuticals

摘　　要：目的评估艾滋病毒(HIV)感染合并终末期肾病患者接受腹膜透析的治疗效果。方法选取2014年7月至2017年5月医院泌尿中心收治的HIV感染合并终末期肾病患者14例。置管后3d开始腹膜透析治疗,检测腹膜透析前及透析1周后脑利钠肽(BNP)。结果腹膜透析1周后,BNP明显降低(P<0.05),残余尿量变化无显著差异(P>0.05)。治疗1个月后,患者血肌酐(SCr)、血尿素氮(BUN)、血钾(K)明显下降(P<0.01),血红蛋白(Hb)、白蛋白(ALB)等指标上升(P<0.05)。所有患者接受高效抗逆转录病毒治疗(HAART),治疗前后CD4+T淋巴细胞无显著变化(P>0.05)。结论腹膜透析用于HIV合并终末期肾病患者疗效显著,安全有效。Objective To evaluate effect of peritoneal dialysis in the treatment of the HIV infected patients with end-stage renal disease(ESRD).Methods Selected 14 HIV infected patients with ESRD in our hospital from July 2014 to May 2017.Started peritoneal dialysis after 3 d of peritoneal dialysis catheter.Detected the BNP before peritoneal dialysis and after peritoneal dialysis for 1 week.The BNP was detected before peritoneal dialysis and after peritoneal dialysis for 1 month.Results After 1 month of peritoneal dialysis,The BNP decreased significantly(P<0.05).There was no significant difference in residual urine volume(P>0.05).There was a significant decrease of serum creatinine(SCr),blood urea nitrogen(BUN),potassium(K)after peritoneal dialysis one month(P<0.01),a rise of hemoglobin(Hb)and ALB(P<0.05).All of the patients received highly active antiretroviral therapy(HAART),CD4+T lymphocyte level has no obvious change(P>0.05).Conclusion The HIV infected patients with ESRD treated with peritoneal dialysis can achieve satisfactory therapeutic effect and safety.

关 键 词：艾滋病毒 感染 终末期肾病 腹膜透析 

分 类 号：R459.5[医药卫生—治疗学] R692[医药卫生—临床医学]