复方萘普生栓联合间苯三酚在绝经期出血妇女行宫腔镜检查中的应用  

Application of Compound Naproxen Suppository combined with Phloroglucinol during hysteroscopic examination in menopausal bleeding women

作　　者：任伟 李立丽 史慧星 张永存 袁红 钱雅丽 崔富春[2] REN Wei;LI Lili;SHI Huixing;ZHANG Yongcun;YUAN Hong;QIAN Yali;CUI Fuchun(Department of Gynecology,General Hospital of Xingtai Mining Group,Hebei Province,Xingtai 054000,China;Department of Gynaecology and Obstetrics,Shijiazhuang Fourth Hospital,Hebei Province,Shijiazhuang 050000,China)

机构地区：[1]河北省邢台市邢台矿业集团总医院妇科,河北石家庄054000 [2]石家庄市第四医院妇产科,河北石家庄050000

出　　处：《中国医药导报》2018年第21期78-81,共4页China Medical Herald

基　　金：河北省医学科学研究课题计划项目(20130634)

摘　　要：目的探讨复方萘普生栓联合间苯三酚在绝经期出血妇女行宫腔镜检查中的应用价值。方法选取2015年12月~2017年5月邢台矿业集团总医院129例绝经期出血患者,按照随机数字表法分为观察组与对照Ⅰ组、对照Ⅱ组,每组各43例。三组均行宫腔镜检查,术前对照Ⅰ组给予复方萘普生栓,对照Ⅱ组给予注射用间苯三酚,观察组给予复方萘普生栓+注射用间苯三酚。对比三组宫颈软化扩张情况、疼痛分级、不良反应发生率。结果观察组宫颈软化扩张情况优于对照Ⅰ组与对照Ⅱ组,差异有统计学意义(P<0.05);观察组软化扩张显效率[69.77%(30/43)]高于对照Ⅰ组与对照Ⅱ组[34.88%(15/43)、39.53%(17/43)],差异有统计学意义(P<0.05);对照Ⅰ组与对照Ⅱ组宫颈软化扩张情况差异无统计学意义(P>0.05);对照Ⅰ组与对照Ⅱ组显效率比较,差异无统计学意义(P>0.05)。观察组疼痛分级优于对照Ⅰ组与对照Ⅱ组,差异有统计学意义(P<0.05);对照Ⅰ组与对照Ⅱ组疼痛分级差异无统计学意义(P>0.05)。三组皮疹、荨麻疹、下腹胀痛、发热发生率比较,差异均无统计学意义(P>0.05)。结论复方萘普生栓联合间苯三酚有利于提高绝经期出血行宫腔镜检查妇女宫颈软化扩张显效率,可有效减轻疼痛程度,且具有一定安全性。Objective To investigate the application value of Compound Naproxen Suppository combined with Phloroglucinol during hysteroscopic examination in menopausal bleeding women.Methods A total of 129 cases of menopausal bleeding patients in General Hospital of Xingtai Mining Group from December 2015 to May 2017 were selected.They were randomly divided into observation group and control group I and control groupⅡ,43 cases in each group.Hysteroscopy was performed in the three groups.The control groupⅠwas given Compound Naproxen Suppository,the control groupⅡwas given Phloroglucinol for injection,and the observation group was given Compound Naproxen Suppositories combined with Phloroglucinol for Injection.The cervical softening and dilatation,pain grading and incidence of adverse reactions were compared among the three groups.Results The cervical softening and dilatation of the observation group was better than that of the control groupⅠand the control groupⅡ,and the difference was statistically significant(P<0.05).The effect rate of softening and dilatation in the observation group[69.77%(30/43)]was higher than that in the control groupⅠand the control groupⅡ[34.88%(15/43),39.53%(17/43)],and the difference was statistically significant(P<0.05).There was no significant difference in cervical softening and dilatation between control groupⅠand control groupⅡ(P>0.05).There was no significant difference in effecfive rate between the control groupⅠand the control groupⅡ(P>0.05).The observation group had better pain classification than the control group,and the difference between the two groups was statistically significant(P<0.05).There was no significant difference in pain classification between the control group I and the control groupⅡ(P>0.05).The incidence of skin rash,urticaria,abdominal pain and fever three groups were compared,the difference was not statistically significant(P>0.05).Conclusion Compound Naproxen Suppository combined with Phloroglucinol is helpful to improve the effective rate of c

关 键 词：绝经期出血 宫腔镜检查 复方萘普生栓 间苯三酚 宫颈软化扩张 疼痛程度 

分 类 号：R711.52[医药卫生—妇产科学]