血管回声跟踪技术评价类风湿关节炎患者的颈动脉粥样硬化发生的相关性  

Evaluation of carotid atherosclerosis in patients with rheumatoid arthritis by echo tracking technique

作　　者：郭迎春[1] 孟令茜 高志云 马星[1] 刘文瑞[1] 杨漪[1] 彭肖 GUO Yingchun;MENG Lingqian;GAO Zhiyun;MA Xing;LIU Wenrui;YANG Yi;PENG Xiao(Department.of Ultrasound,Harrison International Peace Hospital,Hebei Medical University.Hengshui 053000,China)

机构地区：[1]哈励逊国际和平医院超声科,河北衡水053000 [2]哈励逊国际和平医院风湿免疫科,河北衡水053000 [3]衡水市第四人民医院超声科,河北衡水053000

出　　处：《实用医学杂志》2018年第15期2600-2603,共4页The Journal of Practical Medicine

基　　金：衡水市科技计划项目(编号:2016014109Z)

摘　　要：目的探讨血管回声跟踪技术评价类风湿关节炎患者的颈动脉粥样硬化发生的相关性研究。方法选择2016年1月至2017年5月就诊的110例类风湿关节炎患者进行研究,将110例类风湿关节炎患者作为试验组,选择同期在本院进行体检的健康人员100例作为对照组,采用ALOKA Prosoundα10型彩色超声诊断仪测量两组研究对象的弹性模量(Ep)、僵硬度(β)、顺应性(AC)值、脉搏波传导速度(PWVβ)、膨大指数(AI)等颈动脉弹性参数及颈动脉内中膜厚度(IMT),并对各参数的相关性进行分析。结果试验组Ep、β、PWVβ及AI等指标均明显高于对照组,具有统计学意义(P<0.05);试验组AC值明显低于对照组,差异具有统计学意义(P<0.05);试验组的颈动脉内中膜厚度明显高于对照组,差异具有统计学意义(P<0.05);直线相关性分析显示IMT、Ep、β、PWVβ呈正相关(P<0.05);IMT、Ep、β、PWVβ与AC呈负相关(P<0.05)。结论采用血管回声跟踪技术对类风湿关节炎患者颈动脉弹性参数、颈动脉内中膜厚度进行检查,可以在血管壁形态、结构尚未出现影像学特征改变之前通过相关参数变化对患者颈动脉粥样硬化进行判断。Objective To evaluate thecarotid atherosclerosis in patients with rheumatoid arthritis(RA)by echo tracking technique.Methods From Januray 2016 to May 2017,110 patients with RA were selected as experimental group and another 100 healthy people having physical examination during the same period were selected as control group.Measurement of elastic modulus of the two groups using ALOKA Prosoundα10 color ultrasonic diagnostic instrument(Ep),stiffness(β),compliance(AC),pulse wave velocity(PWVβ)and swelling index(AI)and carotid artery elasticity and carotid intima-media thickness(IMT)was performed.And the correlation of each parameter was analyzed.Results The modulus of Ep,β,PWVβand AI of the experimental group were sig-nificantly higher than that of the control group,which showed statistical significance(P<0.05);the AC value of the experimental group was lower than that of the control group and it was statistically significant(P<0.05)and the intima-media thickness of the carotid artery of the experimental group was significantly higher than that of the control group,indicating statistical significance(P<0.05).Linear correlation analysis showed that IMT,Ep,β,PWV beta were positively correlated(P<0.05)but IMT,Ep,β,PWVβwere negatively correlated with AC(P<0.05).Conclusion The carotid echo tracking technique is used to examine the elastic parameters of the carotid artery and the thickness of the middle membrane of the carotid artery in patients with RA.The carotid ath-erosclerosis can be judged by the changes of the related parameters before the change of the imaging features.

关 键 词：血管回声跟踪 类风湿关节炎 颈动脉粥样硬化 颈动脉内中膜厚度 相关性 

分 类 号：R593.22[医药卫生—内科学] R543.4[医药卫生—临床医学]