成都地区成人股骨头坏死流行病学研究  

Epidemiologic Study of Adult Femoral Head Osteonecrosis in Chengdu, China

作　　者：唐涛[1] 苟远涛 唐俊[1] 何舰[1] 牟帅[1] 赵亮[1] 臧振峰 徐练[1] 杨梅[1] 李燕[1] TANG Tao;GOU Yuan-tao;TANG Jun;HE Jian;MOU Shuai;ZHAO Liang;ZANG Zhen-feng;XU Lian;YANG Mei;LI Yan(The Affiliated Hospital of Chongqing Medical University,Sichuan Bayi Rehabilitation Center,Sichuan Provincial Rehabilitation Hospital,Chengdu,Sichuan 610000,China)

机构地区：[1]重庆医科大学附属医院,四川省八一康复中心(四川省康复医院)骨科·骨关节康复科,四川成都市610000

出　　处：《中国康复理论与实践》2018年第8期970-974,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：四川省卫生和计划生育委员会重点课题(No.16ZD042)。

摘　　要：目的调查成都地区成人股骨头坏死的患病情况及发病特征,并进一步探讨相关危险因素。方法 2016年1月至2018年2月,自行设计调查表格,采用入户或现场问卷调查的方式,对544例(797髋)股骨头坏死患者相关因素进行调查,包括患者一般情况、危险因素、诊断、分期及治疗情况等。并在此基础上,对上述因素进行统计分析。结果 544例患者,其中男性392例,女性152例,男女之比为2.58∶1;年龄19~90岁,平均55岁;双侧同时发生股骨头坏死253例(46.51%);初次诊断股骨头坏死中国际骨循环学会分期,Ⅰ期3.64%,Ⅱ期6.15%,Ⅲ期8.41%,Ⅳ期81.81%。病因构成为酒精性(52.39%)、激素性(16.18%)、创伤性(11.58%)、先髋发育不良性(5.88%)及其他类型(13.97%)。结论成都地区成人股骨头坏死男性发病率高于女性;疾病分期以Ⅲ~Ⅳ期所占比例最大;酒精或激素的大量摄入是导致成人股骨头坏死的主要原因,其中男性以酒精性为主,女性以激素性为主。Objective To investigate the morbidity and characteristics of adult osteonecrosis of the femoral head(ONFH)in Chengdu,and to further explore its related risk factors.Methods Self-designed questionnaires were used to collect data by the way of household or field survey.From January,2016 to February,2018,a total of 544 cases(797 hips)diagnosed as ONFH were included in the study.The medical data including general condition,risk factors,diagnosis,disease stages and treatment were collected.Based on the data,the risk factors were analyzed statistically.Results The average age of 544 patients(392 males and 152 females)was 55 years old(range:19 to 90 years);the bilateral incidence was 46.51%(253 cases).The proportion of Association Research Circulation Osseous stages was accounted respectively 3.64%for stage I,6.15%for stage II,8.41%for stage III and 81.81%for stage IV when confirmed ONFH initially.In all the reasons of ONFH,52.39%were alcohol-associated osteonecrosis,16.18%for steroid-induced osteonecrosis,11.58%for traumatic osteonecrosis,5.88%for dysplastic osteonecrosis,and 13.97%for other reasons.Conclusion The incidence of ONFH was higher in men than in women.Stages III-IV accounted for the highest proportion.The high intake of alcohol or overuse of steroid was the leading causes of adult ONFH,among which alcohol-associated osteonecrosis was the main for the males and steroid-induced osteonecrosis for the females.

关 键 词：股骨头 骨坏死 成人 流行病学 危险因素 

分 类 号：R681.8[医药卫生—骨科学]