雅安市住院心房颤动患者的临床特点变化  

Changes of clinical characteristics of hospitalized patients with atrial fibrillation in Yaan

作　　者：黄正林[1] 高月[2] 张海波[1] 任平[1] 龙毅[1] HUANG Zheng-lin;GAO Yue;ZHANG Hai-bo;REN Ping;LONG Yi(Department of Cardiology,The People′s Hospital of Yaan,Yaan,Sichuan 625000,China;Department of Neonatology,The People′s Hospital of Yaan,Yaan,Sichuan 625000,China)

机构地区：[1]雅安市人民医院心内科,四川雅安625000 [2]雅安市人民医院新生儿科,四川雅安625000

出　　处：《岭南心血管病杂志》2018年第4期416-419,共4页South China Journal of Cardiovascular Diseases

摘　　要：目的了解雅安市住院心房颤动患者的临床特点变化。方法回顾性对比分析雅安市人民医院2002年至2005年与2012年至2015年两组时间队列住院心房颤动患者的临床资料。结果 (1)经检索,2002年至2005年队列有466例及2012年至2015年队列有792例心房颤动患者纳入统计;(2)心房颤动患者的主要病因或相关因素比例高低:2002年至2005年队列为老年>原发性高血压(高血压)>吸烟>冠状动脉粥样硬化性心脏病(冠心病)>风湿性心脏病>肥胖,2012年至2015年为老年>高血压>吸烟>冠心病>非缺血性心肌病>慢性呼吸系统疾病。两组队列间比较,病因或相关因素为高血压、风湿性心脏病及先天性心脏病比较,差异有统计学意义(P<0.05);(3)与2002年至2005年队列相比,2012年至2015年的患者抗心律失常药物使用率下降,华法林使用率上升,且CHA2DS2-VASc评分2~3分的华法林使用率最高,但出血风险两组比较,差异无统计学意义(P>0.05)。结论 2002年至2005年队列与2012年至2015年队列分析结果显示,雅安市心房颤动患者最常见的病因或相关因素依然是老年、高血压、吸烟和冠心病,治疗以控制心室率及抗栓为主,华法林的使用率在提高,但仍显不足。Objectives To study the changes of clinical characteristics of hospitalized patients with atrial fibrillation in Yaan.Methods The clinical data of hospitalized patients with atrial fibrillation in The People′s Hospital of Yaan from 2002 to 2005 and from 2012 to 2015 were retrospectively and contrastively analyzed.Results(1)Totally 466 patients in the 2002-2005 cohort and 792 patients in the 2012-2015 cohort were enrolled;(2)The main etiological or associated factors of atrial fibrillation in this study were as follows:senium>hypertension>smoking>coronary atherosclerotic heart disease>rheumatic heart disease>obesity in the 2002-2005 cohort,and senium>hypertension>smoking>coronary atherosclerotic heart disease>non-ischemic cardiomyopathy>chronic lung disease in the 2012-2015 cohort.Factors including hypertension,rheumatic heart disease and congenital heart disease were statistically different between the two cohorts(P<0.05).The usage rates of antiarrhythmic drugs in the 2012-2015 cohort decreased,but the usage of warfarin increased without increasing risk of bleeding,and the usage rates of warfarin in patient with CHA2DS2-VASc 2 to 3 were the highest.Conclusions Among the two cohorts enrolled from 2002 to 2005 and 2012 to 2015,the senium,hypertension,smoking and coronary atherosclerotic heart disease are still the most common etiological or associated factors of atrial fibrillation in Yaan,and the main treatment traits of atrial fibrillation are antithrombotic therapy and ventricular rate control.It is still not enough in spite of increasing usage of warfarin.

关 键 词：心房颤动 住院患者 抗栓治疗 

分 类 号：R541.75[医药卫生—心血管疾病]