溶栓后冠状动脉介入治疗和直接冠状动脉介入治疗急性心肌梗死的疗效和安全性  

Efficacy and safety of interventional therapy(PCI) and direct PCI after thrombolysis in the treatment of acute myocardial infarction

作　　者：宋艳红[1] Song Yanhong(Xinmin people's Hospital internal medicine,Xinmin,Liaoning,110300,China)

机构地区：[1]新民市人民医院内科,辽宁新民110300

出　　处：《当代医学》2018年第24期19-21,共3页Contemporary Medicine

摘　　要：目的研究与探讨溶栓后介入治疗(PCI)和直接PCI治疗对于急性心肌梗死的临床效果及安全性。方法从本院2017年4月~2018年4月期间内接收的急性心肌梗死患者中,随机抽取94例患者,将其分为观察组与对照组,每组47例。对照组患者接受直接PCI进行治疗,观察组患者采用静脉溶栓后介入PCI治疗。观察两组患者治疗后的IRA再通率、ST段下移率、支架植入成功率以及胸痛胸闷症状缓解率;观察两组患者并发症的发生率以及住院死亡率;观察两组患者治疗前后的左心射血分数情况。结果观察组患者治疗后IRA再通率、ST段下移率、支架植入成功率以及胸痛胸闷症状缓解率显著优于对照组患者,差异有统计学意义(P<0.05);观察组患者并发症发生率及住院死亡率均低于对照组患者,差异有统计学意义(P<0.05);观察组患者治疗后左心射血分数显著高于对照组患者,差异有统计学意义(P<0.05)。结论对急性心肌梗死患者进行静脉溶栓后介入PCI治疗的临床效果较为显著,有效的改善了患者的新功能情况,并且较少引起并发症的发生,安全性较高,可以在医学上推广使用。Objective To study the clinical effect and safety of PCI and direct PCI in patients with acute myocardial infarction(AMI).Methods From April 2017 to April 2018,94 patients with acute myocardial infarction were randomly selected and divided into observation group and control group with 47 cases in each group.The patients in the control group were treated with direct PCI,and the patients in the observation group were treated with PCI after intravenous thrombolysis.To observe the rate of IRA recanalization and St segment depression,the success rate of stent implantation and the relief rate of chest pain and chest tightness in the two groups after treatment,and to observe the rate of relief of chest pain and chest tightness in the two groups.The incidence of complications and hospital mortality,left ventricular ejection fraction(LVEF)before and after treatment were observed.Results The IRA recanalization rate,stenting success rate and relief rate of chest pain and chest tightness in the observation group were significantly higher than those in the control group(P<0.05).The incidence of complications and hospital mortality in the observation group were significantly lower than those in the control group(P<0.05),and the left ventricular ejection fraction in the observation group was significantly higher than that in the control group(P<0.05).Conclusion The clinical effect of interventional PCI for patients with acute myocardial infarction after intravenous thrombolytic therapy is significant.It can effectively improve the new function of the patients and cause fewer complications and higher safety.It can be widely used in medicine.

关 键 词：静脉溶栓 冠状动脉介入治疗 急性心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]