红花黄色素联合二甲双胍治疗早期糖尿病肾病的疗效观察  

作　　者：徐小华[1] 首云锋[1] 

机构地区：[1]重庆市巴南区人民医院,400320

出　　处：《湖南中医药大学学报》2018年第A01期84-84,共1页Journal of Hunan University of Chinese Medicine

摘　　要：目的:探讨红花黄色素联合二甲双胍治疗早期糖尿病肾病的疗效。方法:选择2016年1月-2017年3月80例早期糖尿病肾病患者分组。对照组采用二甲双胍治疗,联合治疗组采用红花黄色素联合二甲双胍治疗。比较两组早期糖尿病肾病临床疗效;治疗前后肾炎性因子指标;干预前后患者血液流变学。结果:联合治疗组早期糖尿病肾病临床疗效高于对照组,P<0.05;干预前两组肾炎性因子指标相近,P>0.05,干预后联合治疗组肾炎性因子指标优于对照组,P<0.05;干预前两组血液流变学相近,P>0.05;干预后联合治疗组血液流变学优于对照组,P<0.05。结论:红花黄色素联合二甲双胍治疗早期糖尿病肾病的疗效确切,可有效改善患者血液流变学指标,减轻炎症水平,值得推广。Objective:To investigate the efficacy of safflor yellow combined with metformin in the treatment of early diabetic nephropathy.Methods:From January 2016 to March 2017,80 patients with early diabetic nephropathy were divided into groups.The control group was treated with metformin,and the combined treatment group was treated with safflower yellow combined with metformin.The clinical efficacy of early diabetic nephropathy was compared between two groups.The indexes of nephritic factors before and after treatment and the hemorheology of patients before and after intervention were compared.Results:The clinical efficacy of early diabetic nephropathy in the combined treatment group was higher than that of the control group(P<0.05);nephritis index of the two groups before intervention was similar(P>0.05),nephritis index of the combined treatment group was better than that of the control group(P<0.05).The hemorheology of the two groups before intervention was similar,P>0.05;the hemorheology of the combined treatment group was better than that of the control group after intervention(P<0.05).Conclusion:Safflower yellow combined with metformin treatment of early diabetic nephropathy curative effect is exact,can effectively improve the patient’s hemorheological parameters,reduce the level of inflammation,it is worth promoting.

关 键 词：红花黄色素 二甲双胍 早期糖尿病肾病 疗效 

分 类 号：R587.2[医药卫生—内分泌]