STI评估左心室逆重构扩张型心肌病患儿左心室收缩功能  

STI in evaluation on left ventricular systolic function in children with reverse-remodeled dilated cardiomyopathy

作　　者：肖丽苗 陈文娟[1] 彭颖慧 杨柳 刘倩君 XIAO Limiao;CHEN Wenjuan;PENG Yinghui;YANG Liu;LIU Qianjun(Department of Ultrasound,Hunan Children Hospital,Changsha 410007,China)

机构地区：[1]湖南省儿童医院超声科,湖南长沙410007

出　　处：《中国医学影像技术》2018年第9期1351-1355,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨扩张型心肌病(DCM)患儿左心室逆重构(LVRR)前后左心室局部心功能变化。方法收集24例临床诊断为DCM并经治疗达到LVRR标准的患儿,并选取性别和年龄、体表面积分别与患儿发生LVRR前与发生LVRR后相匹配的各24名健康儿童分别作为对照组1及对照组2。应用STI定量评估受检儿常规超声心功能参数、左心室各节段纵向应变(LS)和圆周应变(CS)。分别比较24例DCM患儿LVRR前与LVRR后、LVRR前与对照组1及LVRR后与对照组2各参数的差异。结果 24例DCM患儿LVRR后LVEDD、LVEDV、LVESV均低于LVRR前,而LVEF、左心室各节段LS及CS均高于LVRR前(P均<0.05)。与对照组1相比,DCM患儿LVRR前左心室各节段LS及CS均降低(P均<0.05);与对照组2相比,DCM患儿LVRR后有12个节段LS及10个节段CS均降低(P均<0.05),其余节段LS与CS与对照组2比较差异均无统计学意义(P均>0.05)。结论 DCM患儿发生LVRR后左心室整体及局部收缩功能较LVRR前有明显好转,但多数左心室节段收缩功能仍未恢复至正常水平。Objective To evaluate the changes of left ventricular systolic function before and after left ventricular reverse-remodeled(LVRR)in children with dilated cardiomyopathy(DCM).Methods Totally 24 children with clinically diagnosed DCM and achieved LVRR after treatment were collected,while 48 healthy children with matched age,sex and body surface area pre-and post-LVRR were enrolled in control group 1(n=24)and control group 2(n=24),respectively.Routine echocardiographic functional parameters,left ventricular longitudinal strain(LS)and circumferential strain(CS)were evaluated with STI.The above parameters between DCM children pre-and post-LVRR,DCM children pre-LVRR and control group 1,as well as DCM children post-LVRR and control group 2 were compared.Results LVEDD,LVEDV,LVESV of DCM children post-LVRR were lower than those of DCM children pre-LVRR,while LVEF,LS and CS of left ventricular were higher than those of DCM children pre-LVRR(all P<0.05).Compared with control group 1,LS and CS decreased in all segments of left ventricular of DCM children pre-LVRR(P<0.05).Compared with control group 2,there were 13 segments of LS and 10 segments of CS decreased of DCM children post-LVRR(P<0.05).There was no significant difference of LS nor CS for remaining segments between DCM children post-LVRR and control group 2.Conclusion Left ventricular systolic function was improved in DCM children after LVRR,but myocardial function of many segments could not return to normal.

关 键 词：心肌病 扩张型 儿童 心室功能 左 心室重构 斑点追踪成像 

分 类 号：R541[医药卫生—心血管疾病] R540.45[医药卫生—内科学]