扩散张量成像在良恶性脑膜瘤鉴别诊断中的初步研究  

Preliminary study of DTI in the differential diagnosis of benign and malignant meningiomas

作　　者：丁伟[1] 王冠[1] 罗莎 Ding Wei;Wang Guan;Luo Sha(Department of Radiology,Benxi Central Hospital,China Medical University,Benxi 117000,China)

机构地区：[1]中国医科大学本溪中心医院放射科,117000

出　　处：《国际医药卫生导报》2018年第17期2624-2626,共3页International Medicine and Health Guidance News

摘　　要：目的 对比研究扩散张量成像平均扩散系数(ADC)和各向异性分数(FA)在良恶性脑膜瘤中的差异,探讨其应用于良恶性脑膜瘤鉴别诊断的价值。方法 选取经手术和病理证实的20例恶性脑膜瘤病例和20例良性脑膜瘤病例,回顾性测量瘤体及肿瘤邻近水肿白质区的ADC值和FA值,对比分析其差异。结果 良、恶性脑膜瘤组瘤体实质区ADC值分别为(0.937±0.069)×10-3mm2/s、(0.689±0.073)×10-3mm2/s,差异有统计学意义(P<0.05);良、恶性脑膜瘤组瘤周水肿区ADC值分别为(1.367±0.064)×10-3mm2/s、(1.706±0.049)×10-3mm2/s,差异有统计学意义(P<0.05);良、恶性脑膜瘤组瘤周水肿区FA值分别为(0.242±0.089)、(0.169±0.024),差异有统计学意义(P<0.05)。结论 扩散张量成像应用于良恶性脑膜瘤鉴别诊断可以为临床提供更多的诊断依据,将其与常规头部磁共振增强检查结合有助于脑膜瘤的术前定性诊断。Objective To study the differential diagnostic values of ADC value and FA value for benign and malignant meningiomas.Methods 20 cases of benign meningiomas and 20 cases of malignant meningiomas who were surgically and pathologically confirmed were retrospectively analyzed.The ADC and FA values of the solid part of tumors and the peritumoral edema were measured and statistically analyzed.Results The ADC value of the solid part of tumors was(0.937±0.069)×10-3mm2/s in benign meningioma group and(0.689±0.073)×10-3mm2/s in malignant meningioma group,with statistically significant difference(P<0.05).The ADC value of the peritumoral edema was(1.367±0.064)×10-3mm2/s in benign meningioma group and(1.706±0.049)×10-3mm2/s in malignant meningioma group,with statistically significant difference(P<0.05).The FA value of the peritumoral edema was(0.242±0.089)in benign meningioma group and(0.169±0.024)in malignant meningioma group,with statistically significant difference(P<0.05).Conclusion Combined with contrast-enhanced MRI,DTI can provide more evidence for clinical diagnosis of benign and malignant meningiomas,which is helpful for preoperative qualitative diagnosis of meningiomas.

关 键 词：扩散张量成像 恶性脑膜瘤 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.45[医药卫生—诊断学]