成人癫痫患者夜间睡眠事件的多导睡眠图分析  

An Analysis of Nocturnal Sleep Events in Adult Patients with Epilepsy by Polysomnogram

作　　者：严金柱[1] 庄小鹏 季晓林[1] 吴美娜[1] 叶华[1] 王小勇[1] YAN Jinzhu;ZHUANG Xiaopeng;JI Xiaolin;WU Meina;YE Hua;WANG Xiaoyong(Department of Neurology,Fujian Province Governmental Hospital, The Affiliated Hospital of Fujian Health College,Fuzhou 350003,China;Department of Clinical Skill Training Center of Fujian Medical University,Fuzhou 350122,China)

机构地区：[1]福建省级机关医院神经内科,福建卫生职业技术学院附属医院,福州350009 [2]福建医科大学临床技能教学中心,福州350122

出　　处：《福建医科大学学报》2018年第3期173-177,共5页Journal of Fujian Medical University

摘　　要：目的探讨癫痫患者的睡眠结构和睡眠相关事件等多导睡眠图特征。方法回顾性分析54例成人(年龄≥16岁)癫痫患者和58例非癫痫患者的含16导脑电图的视频多导睡眠监测图,进一步分析比较癫痫组和对照组、男性和女性癫痫患者的夜间睡眠结构及睡眠相关事件特征。结果 (1)与对照组比较,癫痫组的阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)出现率更高(42.6%vs 13.8%,P<0.05);(2)与女性患者比较,男性患者的体质量指数(BMI)及OSAHS出现率更高[(24.04±2.86)vs(20.08±3.01)kg/m2;54.3%vs 21.1%,P<0.05],而2组间的睡眠结构差别无统计学意义。结论癫痫患者夜间睡眠中OSAHS较常见,在男性肥胖患者中更多见。Objective To explore characteristics of sleep architecture and sleep-related events in epileptics. Methods This was a retrospective study. A total of 54 adult patients(older than 16 years)meeting the clinical diagnostic criteria of epilepsy and 58 non-epileptic patients were included in the study. All subjects underwent overnight ambulatory video-polysomnography with 16 channel electroencephalograph(EEG). We further compared the sleep architecture and sleep-related events between epileptics and normal controls,and between male and female epileptics,separately. Results (1)Compared with controls,the prevalence of OSAHS was higher in epileptic patients(42.6%vs 13.8%,P<0.05). (2)Compared with female epileptics,the prevalence of OSAHS was higher in male epileptics with higher body mass index(BMI)[54.3%vs 21.1%,(24.04±2.86)vs(20.08±3.01)kg/m 2,P<0.05]. There was no significant difference in sleep architecture between the two groups. Conclusion There is a higher prevalence of OSAHS in epileptics,especially in male obese patients.

关 键 词：癫痫 多导睡眠描记术 入睡和睡眠维持障碍 睡眠 睡眠呼吸暂停 阻塞性 

分 类 号：R338.63[医药卫生—人体生理学] R444[医药卫生—基础医学]