芬兰版和中国版糖尿病风险评估量表在新疆社区糖尿病筛查中的应用价值比较研究  

Finnish Diabetes Risk Score and Chinese Diabetes Risk Score for Community-based Screening of Diabetes inXinjiang:a Comparative Study

作　　者：张春桃 苏银霞[2] 王淑霞[2] 王育珊[2] 周红 魏君[1] 姚华[2] 李豫凯[4] ZHANG Chun-tao;SU Yin-xia;WANG Shu-xia;WANG Yu-shan;ZHOU Hong;WEI Jun;YAO Hua;LI Yu-kai(School of Public Health,Xinjiang Medical University,Urumqi 830054,China;Physical Management Center,Xinjiang Medical University,Urumqi 830054,China;Center for Disease Control and Prevention of Urumqi High-tech Industrial Development Zone,Urumqi 830054,China;Party School Office,Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学公共卫生学院,新疆乌鲁木齐市830054 [2]新疆医科大学健康管理中心,新疆乌鲁木齐市830054 [3]新疆乌鲁木齐市新市区疾病预防控制中心,830054 [4]新疆医科大学党校办,新疆乌鲁木齐市830054

出　　处：《中国全科医学》2018年第25期3079-3083,共5页Chinese General Practice

基　　金：自治区重点研发项目(2016B03048)

摘　　要：目的比较芬兰版和中国版糖尿病风险评估量表在新疆社区糖尿病筛查中的应用价值,为新疆社区糖尿病筛查提供理论依据。方法于2017年5月采用多阶段随机抽样法,在新疆乌鲁木齐市抽取18~75岁社区居民1 680例。分别采用芬兰版和中国版糖尿病风险评估量表对纳入居民进行筛查,并以口服葡萄糖耐量试验(OGTT)结果作为诊断糖尿病的"金标准",比较两种评估量表的灵敏度、特异度、约登指数等指标以及受试者工作特征(ROC)曲线下面积。结果完成量表评价和OGTT的社区居民共1 649例,OGTT共检出2型糖尿病患者402例(24.38%),非糖尿病患者1 247例(75.62%)。芬兰版(9分)和中国版(25分)糖尿病风险评估量表在诊断切点时的灵敏度分别为88.81%、79.85%,特异度分别为61.59%、40.66%,约登指数分别为0.50、0.21。芬兰版和中文版糖尿病风险评估量表在社区糖尿病筛查中的ROC曲线下面积分别为0.833[95%CI(0.813,0.854]、0.634[95%CI(0.604,0.663)],芬兰版高于中国版,差异有统计学意义(P<0.05)。结论芬兰版糖尿病风险评估量表在新疆社区糖尿病筛查中的诊断准确性较中国版量表高,是评估新疆社区居民糖尿病患病风险的可靠筛查工具。Objective To compare the performance of Finnish Diabetes Risk Score(FINDRISC)with that of Chinese Diabetes Risk Score(CDRISC)in community-based screening of diabetes in Xinjiang,providing a theoretical basis for this kind of screening in this area.Methods By multi-stage random sampling,1 680 community-dwelling residents aged 18-75 years were recruited from Urumqi of Xinjiang in May 2017.FINDRISC,CDRISC and OGTT(gold standard for the diagnosis of diabetes)were used to screen diabetes risk,and the results of the former two were compared in terms of sensitivity,specificity,Youden's index,as well as the area under the ROC curve(AUC),and were compared with the OGTT results.Results A total of 1 649 residents completed the 3 tests.By OGTT,402(24.38%)were found with type 2 diabetes,other 1 247(75.62%)without diabetes.In screening diabetes risk,the sensitivity,specificity and Youden's index were 88.81%,61.59%,0.50,respectively for FINDRISC with an identified optimal cut-off point of 9 points,and were 79.85%,40.66%,0.21 respectively for CDRISC with an identified optimal cut-off point of 25 points.Moreover,FINDRISC demonstrated a larger AUC than CDRISC in the screening{0.833〔95%CI(0.813,0.854)〕vs 0.634〔95%CI(0.604,0.663)〕}(P<0.05).Conclusion As being more accurate than CDRISC,FINDRISC is reliable for community-based screening of diabetes in Xinjiang.

关 键 词：糖尿病 2型 筛查 糖尿病风险评估量表 新疆 

分 类 号：R587.1[医药卫生—内分泌]