吡嗪双腙配体铜配合物的合成、结构和DNA结合性质（英文）  

Synthesis, Crystal Structure and DNA Interaction of a Cu(Ⅱ) Complex with Bis-hydrazone Ligand Bearing Pyrazine Unit

作　　者：吴浩 赵晓雷 钟润斌 代耿耿 吴伟娜 王元 WU Hao;ZHAO Xiao-Lei;ZHONG Run-Bin;DAI Geng-Geng;WU Wei-Na;WANG Yuan(College of Chemistry and Chemical Engineering,Henan Key Laboratory of Coal Green Conversion,Henan Polytechnic University,Jiaozuo,Henan 454000,China)

机构地区：[1]河南理工大学化学化工学院,河南省煤炭绿色转化重点实验室,焦作454000

出　　处：《无机化学学报》2018年第10期1917-1922,共6页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.21001040)和河南省自然科学基金(No.182300410183,162300410011)资助项目。

摘　　要：合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Cu_4(L)_2(CH_3O)_2(CH_3OH)_4(SO_4)_2]SO_4·6CH_3OH (1)的结构(L为3-乙基-2-乙酰吡嗪双缩水合肼)。单晶衍射结果表明,在配合物1中,每个Cu(Ⅱ)离子与来自半个腙配体的2个N原子和分别来自配位甲醇、桥联甲氧基及2个不同硫酸根的单齿配位和桥联氧原子配位,形成扭曲的八面体配位构型。4个Cu(Ⅱ)离子通过对称操作形成理想的平面四核铜簇。此外,荧光光谱表明配合物1与DNA的相互作用强于配体L。A complex,namely[Cu4(L)2(CH3O)2(CH3OH)4(SO4)2]SO4·6CH3OH(1)(L=N,N′-bis-(1-(3-ethyl-pyrazin-2-yl)-ethylidene)-hydrazine)has been synthesized and characterized by single-crystal X-ray diffraction,elemental analysis and IR spectroscopy.X-ray diffraction analysis results show that in complex 1,each Cu(Ⅱ)center with a distorted octahedron geometry is coordinated by two N atoms from one pyrazin-2-yl-ethylideneamine subunit,and four O atoms involving one O atom from one neutral methanol,oneμ2-bridged O atom from one methoxy anion,oneμ2-bridged O and one monodentate O atoms from two independent sulfate anions,thus forming an ideal planar four-membered Cu4 core.In addition,the fluorescence spectra indicate that the interaction of complex 1 with DNA is stronger than that of the ligand L.CCDC:1844807,L;1844806,1.

关 键 词：双腙 晶体结构 Cu(Ⅱ)离子配合物 DNA相互作用 吡嗪 

分 类 号：O614.121[理学—无机化学]