天然杀伤细胞在肿瘤免疫治疗中的研究进展  

Recent research progress on natural killer cells in tumor immunotherapy

作　　者：方广 黄韧[2] FANG Guang;HUANG Ren(Pharmacology Department,Guangdong medical university,Zhanjiang,Guangdong 524023,China;Guangdong laboratory animals monitoring institute,Guangdong Key Laboratory of Laboratory Animal Guangzhou,Guangdong 510663)

机构地区：[1]广东医科大学,广东湛江524045 [2]广东省实验动物监测所,广州510663

出　　处：《中国实验动物学报》2018年第5期656-661,共6页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家自然科学基金(31272389);广东省科技计划(2017A070702001)~~

摘　　要：目前,免疫疗法在许多癌症治疗中显示出显著的疗效。在癌症免疫监视的早期阶段,天然杀伤细胞在识别和根除肿瘤中发挥关键作用,可见其在癌症治疗中存在巨大的潜力。本文对目前天然杀伤细胞抗瘤作用的研究进程、作用机制以及临床治疗方式进行总结,已期为未来天然杀伤细胞在肿瘤治疗中的应用或者基础研究提供参考。Immunotherapy has shown significant efficacy in the treatment of many tumors.Natural killer cells play a key role in the identification and eradication of tumors and have great potential for tumor treatment.This paper summarizes the progress of research on natural killer cells as well as their mechanism of action and associated clinical treatments,providing a reference for future applications and basic research on the use of natural killer cells in tumor therapy.

关 键 词：肿瘤 免疫治疗 天然杀伤细胞 固有免疫 

分 类 号：Q95-33[生物学—动物学]