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作 者:梁展维 LIANG Zhanwei(Department of Pediatric Surgery,Guangzhou Huadu Maternal and Child Health Care Hospital,Guangzhou 510800,China)
机构地区:[1]广州市花都区妇幼保健院小儿外科,510800
出 处:《中国现代药物应用》2018年第20期11-12,共2页Chinese Journal of Modern Drug Application
摘 要:目的研究小儿肠套叠采用空气灌肠整复治疗的效果。方法 100例肠套叠患儿,根据治疗方法不同分为对照组和观察组,每组50例。对照组实施水压灌肠复位,观察组实施空气灌肠整复。比较两组患儿的复位成功率、复位时间、便血恢复时间、住院时间,以及治疗前后肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平。结果两组患儿复位成功率、便血恢复时间、住院时间比较,差异无统计学意义(P>0.05),观察组患儿复位时间为(5.50±2.27)min,明显短于对照组的(10.35±4.14)min,差异有统计学意义(P<0.05)。治疗前,两组患儿TNF-α、IL-6水平比较,差异无统计学意义(P>0.05);治疗后,观察组患儿TNF-α、IL-6水平低于对照组,差异具有统计学意义(P<0.05)。结论空气灌肠整复、水压灌肠复位治疗小儿肠套叠的复位成功率均较高,但空气灌肠整复的复位时间更短,可促进炎性因子水平改善,临床上需根据患儿的实际情况选择合适的治疗方法。Objective To research the efficacy of air enema reduction in the treatment of pediatric intussusception.Methods A total of 100 cases of pediatric intussusception were divided into control group and observation group according to different treatment methods,50 cases in each group.The control group was treated with hydrostatic pressure enema reduction,the observation group was treated with air enema reduction.The successful reduction rate,reduction time,recovery time of hematochezia,length of stay,the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)before and after treatment between the two groups were compared.Results There were no significant differences in the successful reduction rate,recovery time of hematochezia and length of stay between the two groups(P>0.05).The reduction time of the observation group was(5.50±2.27)min,which was significantly shorter than(10.35±4.14)min of the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the levels of TNF-αand IL-6 between the two groups(P>0.05).After treatment,the levels of TNF-αand IL-6 in the observation group were significantly lower than those in the control group,the differences were statistically signficant(P<0.05).Conclusion The successful rate of air enema reduction and hydrostatic pressure enema reduction in the treatment of pediatric intussusception are higher,but the reduction time of air enema reduction is shorter,it can promote the improvement of inflammatory factors.It is necessary to choose the appropriate treatment method according to the actual situation of children.
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