马来海松酸长链烷基酰(亚)胺钠的合成及其对小地老虎的拒食活性研究  

Synthesis of Sodium Maleopimaric Acid Long Chain Alkyl( Alkylene) Amines and Their Antifeedant Activity Against Agrotis ypsilon

作　　者：翟兆兰 闫鑫焱 许吉 宋湛谦 商士斌[1,2] 饶小平[1,2] ZHAI Zhaolan;YAN Xinyan;XU Ji;SONG Zhanqian;SHANG Shibin;RAO Xiaoping(Institute of Chemical Industry of Forest Products,CAF;National Engineering Lab.for Biomass Chemical Utilization;Key and Open Lab.of Forest Chemical Engineering,SFA;Key Lab.of Biomass Energy and Material,Jiangsu Province, Nanjing 210042,China;Research Institute of Forestry New Technology,CAF,Beijing 100091,China)

机构地区：[1]中国林业科学研究院林产化学工业研究所,生物质化学利用国家工程实验室,国家林业局林产化学工程重点开放性实验室,江苏省生物质能源与材料重点实验室,江苏南京210042 [2]中国林业科学研究院林业新技术研究所,北京100091

出　　处：《林产化学与工业》2018年第5期23-29,共7页Chemistry and Industry of Forest Products

基　　金：国家自然科学基金资助项目(31470596)。

摘　　要：以马来海松酸、十二胺、十四胺、十六胺和十八胺为主要原料,经酰胺化和酸碱中和反应合成了马来海松酸酰胺二钠(C_n-MPA-2Na,n=12,14,16,18),采用IR和1H NMR对产物的结构进行了表征,并采用浸叶法研究了C_n-MPA-2Na及文献合成的马来海松酸酰亚胺钠(C_n-MPA-Na,n=12,14,16)对小地老虎的拒食活性。结果表明:室温下,C_n-MPA-2Na和C_n-MPA-Na均具有良好的水溶性,且C_n-MPA-2Na在水中的溶解度大于300 g/L。水溶性的马来海松酸长链烷基酰(亚)胺钠中烷烃链长和羧酸钠个数对小地老虎拒食活性均无明显影响,其中C_(12)-MPA-2Na、C_(18)-MPA-2Na和C_(14)-MPA-Na对小地老虎具有较强的拒食活性,其拒食中浓度(AFC_(50))分别为0.51、0.54和0.77 g/L。With maleopimaric acid,dodecylamine,tetradecylamine,hexadecylamineand octadecylamine as the main raw materials,disodium maleopimaric acid amide(C n-MPA-2Na,n=12,14,16,18)were synthesized through amidation reaction and acid-base neutralization,and their structures were characterized by IR and 1H NMR.The antifeedant activities of C n-MPA-2Na(n=12,14,16,18)and sodium maleopimaric acid long chainalkylene amines(C n-MPA-Na,n=12,14,16)reported in reference against Agrotis ypsilon were investigated using the method of leaf disc.The results showed that both C n-MPA-2Na(n=12,14,16,18)and C n-MPA-Na(n=12,14,16)show good water solubility at room temperature,and the solubility of C n-MPA-2Na was above 300 g/L.Both the length of alkane and the number of sodium carboxylate in soluble sodium maleopimaric acid long chain alkyl(alkylene)amines showed little influences on its antifeedant activities against A.ypsilion.And C 12-MPA-2Na,C 18-MPA-2Na and C 14-MPA-Na showed strong antifeedant activities against A.ypsilon.The 50%antifeedant concentrations(AFC 50)for C 12-MPA-2Na,C 18-MPA-2Na and C 14-MPA-Na were 0.51,0.54 and 0.77 g/L,respectively.

关 键 词：马来海松酸 合成 小地老虎 水溶性 拒食活性 

分 类 号：TQ35[化学工程]