贵州毕节地区燃煤污染型氟中毒病区人群身高与血浆氟含量的相关性研究  

Correlation between population height and concentration of plasma fluorine from coal-burning endemic fluorosis area in Bijie,Guizhou

作　　者：王婵娟[1,2] 何燕 张婷[1,2] 禹文峰 官志忠[1,2] 安宇 Wang Chanjuan;He Yan;Zhang Ting;Yu Wenfeng;Guan Zhizhong;An Yu(Key Laboratory of Endemic and Ethnic Diseases(Guizhou Medical University),Ministry of Education, Guiyang 550004;Key Laboratory of Medical Molecular Biology(Guizhou Medical University),Guiyang 550004;Center Laboratory of Guizhou Provincial People's Hospital,Guiyang 550002)

机构地区：[1]地方病与少数民族疾病教育部重点实验室(贵州医科大学),贵阳550004 [2]贵州省医学分子生物学重点实验室,贵阳550004 [3]贵州省人民医院中心实验室,贵阳550002

出　　处：《环保科技》2018年第5期30-32,60,共4页Environmental Protection and Technology

基　　金：贵州省卫生计生委科学技术基金(gzwjkj2014-1-002);贵州省科技厅科学技术基金(黔科合J字[2013]2040号);贵州省科技厅国际合作项目(黔科合G字[2011]7038号);贵州省科技厅科学技术基金(黔科合J字[2013]2177号);贵州省科技厅科技创新人才团队建设项目(黔科合平台人才[2016]5612);贵州省教育厅自然科学研究项目(黔教合KY字(2012)072号)

摘　　要：目的:研究贵州毕节地区燃煤污染型氟中毒病区人群身高与血浆氟含量的相关性。方法:以贵州毕节地区燃煤污染型地方性氟中毒干预区与非干预区人群以及非病区健康人群作为研究对象,进行身高体重等体格检查。采集静脉全血,使用离子选择性电极测定血浆氟含量,并分析其与身高的相关性。结果:非干预组人群的血浆氟浓度显著的高于干预组(p <0. 05),且两组都极显著的高于对照组(p <0. 01)。男性非干预组人群的身高显著的矮于干预组(p <0. 05),且两组都显著的矮于对照组(p <0. 05)。而女性中非干预组与干预组人群身高相比没有统计学差异(p>0. 05),但两组都显著的矮于对照组(p <0. 05)。非干预组中人群的身高和血浆氟浓度呈负相关(p<0. 01)。结论:本研究所调查的人群中氟中毒非干预区对应的血浆氟含量高于干预区,同时两者又高于非病区,人群身高和血浆氟浓度具有一定的相关性。Objective:To study the correlation between population height and concentration of plasma fluorine from coal-burning endemic fluorosis area in Bijie,Guizhou.Methods:Physical examinations such as height and weight were performed on candidates from the interventional and non-intervention area of coal-fired endemic fluorosis in the Bijie of Guizhou Province and control area.Whole blood was collected and the concentration of plasma fluorine was measured using ion-selective electrodes,and the correlation with the height of the population was analyzed.Results:The plasma fluoride concentration in the non-intervention group was significantly higher than that in the intervention group(p<0.05),and both groups were significantly higher than the control group(p<0.01).The height of the male non-intervention group was significantly shorter than that of the intervention group(p<0.05),and both groups were significantly shorter than the control group(p<0.05).There was no statistically significant difference in height between women in the non-intervention group and the intervention group(p>0.05),but both groups were significantly shorter than the control group(p<0.05).The height of the population in the non-intervention group was negatively correlated with plasma fluoride concentration(p<0.05).Conclusion:The concentration of plasma fluorine in the non-intervention area of the fluorosis population in this study is higher than that in the intervention area.The population height and plasma fluoride concentration are significant correlation.

关 键 词：人群身高 血浆氟含量 燃煤污染型氟中毒 

分 类 号：X503.1[环境科学与工程—环境工程] R12[医药卫生—环境卫生学]