轻型颅脑创伤的神经影像学研究进展  

Research progress on the neuroimaging of mild traumatic brain injury

作　　者：罗慧 杨光博 符锋[3] 孙洪涛[3] 令狐海瑞[3] LUO Hui;YANG Guangbo;FU Feng;SUN Hongtao;LINGHU Hairui(Department of Anesthesiology,Affiliated Hospital of the Logistics College of Armed Police Force,Tianjin 300162,China;Health Team,Service Support Brigade,Huzhou Detachment,Zhejiang Provincial Corps,Chinese People′s Armed Police Force,Zhejiang Province,Huzhou 313000,China;Department of Neurological Diseases,Affiliated Hospital of the Logistics College of Armed Police Force,Tianjin 300162,China)

机构地区：[1]武警后勤学院附属医院麻醉二科,天津300162 [2]武警浙江总队湖州支队勤务保障大队卫生队,浙江湖州313000 [3]武警后勤学院附属医院神经危重症科,天津300162

出　　处：《中国医药导报》2018年第30期19-23,共5页China Medical Herald

基　　金：国家自然科学基金资助项目(81471275)

摘　　要：轻型颅脑创伤(mTBI)可导致大脑结构或功能改变,表现为局灶性神经、认知或行为功能障碍。目前mTBI的诊断标准是非常有限的、可变的,且多基于主观的自我报告,因此限制了临床医生的准确诊断、治疗方案制订和预后评估等。高级神经影像学技术的发展,使客观化评估mTBI成为可能。本文将综述几项颇有前景的成像技术及其应用,以了解mTBI后的大脑异常改变。这些成像方式包括理解大脑结构和组织结构、监测局部血流、评估微出血、测量脑功能及代谢情况的技术。Mild traumatic brain injury(mTBI)can lead to changes in brain structure or function,manifested as focal neurological,cognitive or behavioral dysfunction.At present,the diagnostic criteria of mTBI is very limited,variable,and mostly based on subjective self-reporting,which limits the clinician's accurate diagnosis,treatment plan formulation,and prognostic evaluation.The development of advanced neuroimaging has made it possible to objectively evaluate mTBI.This article reviews several promising imaging techniques and their applications to understand abnormal brain changes after mTBI.These imaging modalities include understanding of brain structure and tissue structure,monitoring of local blood flow,assessment techniques for microbleeds,measurement of brain function,and metabolic techniques.

关 键 词：轻型颅脑创伤 神经影像学 诊断 大脑结构 

分 类 号：R651.1[医药卫生—外科学]