红藤灌肠液水煎剂与免煎颗粒剂的体外抑菌效果比较  

Comparison of antibacterial effect in vitro of Hongteng Enema Decoction and Decoction-free Granules

作　　者：江莉[1] 李玥婷 胡君 李渊[1] 陈会[2] JIANG Li;LI Yue-ting;HU Jun;LI Yuan;CHEN Hui(Department of Pharmacy,Maternal and Child Health Hospital,Jiangxi Province,Nanchang 330006,China;Clinical Laboratory,People′s Hospital,Jiangxi Province,Nanchang 330006,China)

机构地区：[1]江西省妇幼保健院药剂科,江西南昌330006 [2]江西省人民医院检验科,江西南昌330006

出　　处：《中国当代医药》2018年第30期27-29,共3页China Modern Medicine

基　　金：江西省卫生计生委中医药科研立项课题(2016A065)

摘　　要：目的比较红藤灌肠液水煎剂与免煎颗粒剂体外抑菌效果。方法采用纸片扩散法测定红藤灌肠液水煎剂与免煎颗粒剂对金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌、白色假丝酵母菌的体外抑菌作用,通过测量抑菌圈直径考察两种不同剂型的抑菌效果。结果红藤灌肠液水煎剂与免煎颗粒剂对白色假丝酵母菌均无抑菌作用。红藤灌肠液水煎剂对于金黄色葡萄球菌和大肠埃希菌的抑菌圈直径大于免煎颗粒剂,差异有统计学意义(P<0.05);红藤灌肠水煎液对铜绿假单胞菌的抑菌圈直径小于红藤灌肠免煎颗粒剂,差异有统计学意义(P<0.05)。结论红藤灌肠液水煎液与免煎颗粒剂的体外抑菌作用相似,对金黄色葡萄球菌、大肠埃希菌,红藤灌肠水煎液的抑菌效果优于免煎颗粒,对铜绿假单胞菌,红藤灌肠免煎颗粒的抑菌效果优于水煎液。Objective To compare the antibacterial effects in vitro of Hongteng Enema Decoction and Decoction-free Granules.Methods The paper-diffusion method was used to determine the in vitro antibacterial activity of Hongteng Enema Decoction and Decoction-free Granules on Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans.The antibacterial effects of the two different dosage forms were examined by measuring the diameter of the inhibition zone.Results Hongteng Enema Decoction and Decoction-free Granules had no antibacterial effects on Candida albicans.For Staphylococcus aureus and Escherichia coli,the diameter of the inhibition zone of Hongteng Enema Decoction was bigger than that of Decoction-free Granule,and there was a significant difference between them(P<0.05).For Pseudomonas aeruginosa,the diameter of the inhibition zone of Hongteng Enema Decoction was lower than that of Decoction-free Granule,and there was a significant difference between them(P<0.05).Conclusion Hongteng Enema Decoction and Decoction-free Granule have similar antibacterial effects in vitro.The antibacterial effect of Hongteng Enema Decoction against Staphylococcus aureus and Escherichia coli is better than that of Decoction-free Granule.For Pseudomonas aeruginosa,the antibacterial effects of Hongteng Enema Decoction-free Granule is better than that of the Hongteng Enema Decoction.

关 键 词：红藤灌肠液 中药水煎剂 中药免煎颗粒 体外抑菌效果 

分 类 号：R285.5[医药卫生—中药学]