胺碘酮治疗急性心肌梗死后室性心律失常的效果  

Effect of Amiodarone on Ventricular Arrhythmia after Acute Myocardial Infarction

作　　者：林春锦[1] 游哲斌[1] 魏硕[1] 何玲玲[1] 郭太林[1] 周密[2] LIN Chun-jin;YOU Zhe-bin;WEI Shuo;HE Ling-ling;GUO Tai-lin;ZHOU Mi(Department of Geriatrics,Fujian Provincial Hospital,Fujian Provincial Institute of Clinical Geriatrics,Fujian Medical University,Fuzhou,Fujian Province,350001 China;Department of Geriatrics,Fujian Provincial Hospital,Fuzhou,Fujian Province,350001 China)

机构地区：[1]福建省立医院老年科福建省临床老年病研究所福建医科大学省立临床医学院,福建福州350001 [2]福建省立医院老年科,福建福州350001

出　　处：《中外医疗》2018年第29期118-120,共3页China & Foreign Medical Treatment

摘　　要：目的探析胺碘酮治疗急性心肌梗死后室性心律失常的临床治疗效果。方法方便选取2017年5月—2018年4月期间该院收治的66例急性心肌梗死后室性心律失常患者,随机分为2组,将应用利多卡因治疗的33例纳入对照组,将应用胺碘酮治疗的33例患者纳入观察组,对比经7 d治疗后患者的临床治疗效果、不良反应以及心功能指标。结果在总有效率方面比较,观察组96.97%高于对照组(χ~2=6.304 1,P<0.05);在不良反应率方面比较,观察组6.06%低于对照组,(χ~2=5.345 5,P<0.05);在心功能指标方面,观察组的QRS时间(0.138±0.025)s、RP间隔(0.159±0.007)s、HR(86.29±10.67)次/min、LVEF(52.67±5.29)%四项指标均优于对照组;2组数据比较差异有统计学意义(t=4.513 8、6.033 2、15.508 8、13.074 9,P<0.05)。结论急性心肌梗死后室性心律失常患者应用胺碘酮治疗效果显著,可使患者的心功能指标有效改善,不良反应率较低,具有较高的用药安全性,值得临床推广普及。Objective To analyze the clinical effect of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction.Methods 66 patients with acute myocardial infarction and ventricular arrhythmia admitted between May 2017 and April 2018 were convenient selected and randomly divided into two groups.33 patients treated with lidocaine were included in the control group and treated with amiodarone.33 patients were included in the observation group to compare the clinical outcomes,adverse reactions,and cardiac function indicators after 7 days of treatment.Results In terms of total effective rate,the observation group was 96.97%higher than the control group(χ2=6.304 1,P<0.05).In the aspect of adverse reaction rate,the observation group was 6.06%lower than the control group(χ2=5.345 5,P<0.05);In terms of functional indicators,the observation group's QRS time(0.138±0.025)s,RP interval(0.159±0.007)s,HR(86.29±10.67)times/min,and LVEF(52.67±5.29)%were all better than the control group;the difference between the two groups was significant(t=4.513 8,6.033 2,15.508 8,13.0749,P<0.05).Conclusion Patients with ventricular arrhythmia after acute myocardial infarction have significant amiodarone treatment,which can improve the heart function index,lower the adverse reaction rate,and have higher drug safety.It is worthy of clinical popularization.

关 键 词：胺碘酮 急性心肌梗死 室性心律失常 

分 类 号：R542[医药卫生—心血管疾病]