超微血流显像技术对脑梗塞患者颈动脉斑块的诊断及预警价值  

Diagnostic and Early Warning Value of Superb Micro-vascular Imaging on Carotid Plaques in Patients with Cerebral Infarction

作　　者：郭静文[1] 王满立[1] 郭汉涛[1] 裴书芳[1] 陈越峰[1] GUO Jing-wen;WANG Man-li;GUO Han-tao;PEI Shu-fang;CHEN Yue-feng(Department of Ultrasound,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China)

机构地区：[1]广东省人民医院超声科广东省科学医学院,广州510080

出　　处：《循证医学》2018年第5期290-293,共4页The Journal of Evidence-Based Medicine

摘　　要：目的应用超微血流显像技术比较脑梗塞患者与健康体检者颈动脉硬化病变情况的差异,探讨超微血流显像技术在颈动脉病变中的诊断价值。方法研究组选取广东省人民医院住院的脑梗塞患者50例,同时选取50例健康体检者作为对照组,两组均行常规颈动脉扫查,记录颈动脉斑块的位置、大小、形态、内部回声、数目,并对颈动脉斑块行超微血流显像检查,观察斑块内新生血管的情况,比较脑梗塞患者与健康体检者颈动脉斑块的发生及斑块内新生血管检出率的差异。结果脑梗塞患者颈动脉斑块大部分为不规则的软斑(58%,29/50)及混合斑(40%,21/50),并伴有不同程度的颈动脉狭窄(重度狭窄发生率为22.0%),且斑块内新生血管的检出率明显高于健康体检者(c2=12.70,P<0.05)。结论运用超微血流显像技术能对颈动脉斑块的稳定性做出有效评价,指导临床采取正确的预防和治疗措施,预防或减少脑卒中事件的发生。Objectives To investigate the difference of carotid atherosclerosis between patients with cerebral infarction and healthy subjects by superb micro-vascular imaging(SMI),and to evaluate the diagnostic value of SMI in carotid artery lesions.Methods The research group selected 50 patients with cerebral infarction in our hospital,and 50 healthy people were selected as control group,two groups were performed with conventional carotid artery scan and recorded carotid plaque location,size,shape,internal echo,and the number of carotid plaques.Use SMI to observe the plaque of neovascular situation,comparison of plaque of patients with cerebral infarction and healthy subjects on carotid plaque neovascularization in detection rate.Results Most of the carotid plaques in the patients with cerebral infarction were irregular soft spots(58%,29/50)and mixed plaque(40%,21/50),accompanied by different degrees of carotid stenosis(the incidence of severe stenosis was 22%),and the detection rate of neovascularization in the plaque was significantly higher than that of the healthy persons(X2=12.70,P<0.05).Conclusions Using SMI technology can effectively evaluate the stability of carotid plaque,guide the clinical practise to take the correct prevention and treatment measures to prevent or reduce the occurrence of stroke events.

关 键 词：超微血流显像 脑梗塞 颈动脉病变 

分 类 号：R445.1[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]