针刺联合敷脐及西药防治铂类化疗所致迟发性呕吐疗效观察  

Therapeutic Observation of Acupuncture plus Umbilicus Application and Western Medication for Delayed Emesis Induced by Platinum-based Chemotherapy

作　　者：谢腾 王一红 毛咏旻[3] 沈科利 叶帅 沈文姣 吴坚刚 XIE Teng;WANG Yi-hong;MAO Yong-min;SHEN Ke-li;YE Shuai;SHEN Wen-jiao;WU Jian-gang(Zhejiang Elderly Care Hospital,Hangzhou 310015,China;Hangzhou Shangcheng District Xiaoying Street Community Health Service Center,Hangzhou 310009,China;The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China)

机构地区：[1]浙江老年关怀医院,杭州310015 [2]杭州市上城区小营街道社区卫生服务中心,杭州310009 [3]杭州师范大学附属医院,杭州310015

出　　处：《上海针灸杂志》2018年第11期1235-1238,共4页Shanghai Journal of Acupuncture and Moxibustion

基　　金：杭州市医学重点专科专病项目(20150733Q23)

摘　　要：目的观察针刺联合敷脐及西药防治铂类化疗所致迟发性呕吐的临床疗效。方法 64例化疗后迟发性呕吐患者随机分为观察组和对照组,每组32例。对照组采用常规西药治疗,观察组在对照组的基础上采用针刺联合敷脐治疗。观察两组治疗前、治疗2 d后和治疗5 d后MASCC止吐工具中呕吐次数、恶心评分和卡氏评分变化,并比较两组临床疗效。结果治疗2 d后,观察组呕吐次数及恶心评分优于对照组(P<0.05);治疗5 d后两组呕吐次数及恶心评分低于治疗2 d后(P<0.05),观察组优于对照组(P<0.05)。观察组治疗2 d后和5 d后卡氏评分优于对照组(P<0.05)。观察组总有效率为93.8%,对照组为75.0%,两组比较差异有统计学意义(P<0.05)。结论针刺联合敷脐及西药能改善化疗后迟发性呕吐患者恶心呕吐症状和生活能力,提高患者的生存质量。Objective To observe the clinical efficacy of acupuncture plus umbilicus application and Western medication in treating delayed emesis induced by platinum-based chemotherapy.Method Sixty-four patients with chemotherapy-induced delayed emesis were randomized into an observation group and a control group,with 32 cases in each group.The control group was intervened by conventional Western medication,while the observation group was additionally given acupuncture plus umbilicus application.The changes in the scores of vomiting frequency and nausea from the Multinational Association of Supportive Care in Cancer(MASCC)Antiemesis Tool(MAT)and Karnofsky performance score(KPS)were observed before the treatment and after 2-day and 5-day treatment.The clinical efficacies were compared between the two groups.Result After 2-day treatment,the scores of vomiting frequency and nausea in the observation group were better than those in the control group(P<0.05);the scores of vomiting frequency and nausea after 5-day treatment were lower than those after 2-day treatment in the two groups(P<0.05),and the observation group was superior to the control group(P<0.05).The KPS scores after 2-day treatment and after 5-day treatment in the observation group were superior to the control group(P<0.05).The total effective rate was 93.8%in the observation group versus 75.0%in the control group,and the between-group difference was statistically significant(P<0.05).Conclusion Acupuncture plus umbilicus application and Western medication can improve the nausea and vomiting symptoms and living ability in patients with chemotherapy-induced delayed emesis,and improve their quality of life.

关 键 词：针刺疗法 敷脐 针药并用 呕吐 肿瘤 药物相关副作用及不良反应 

分 类 号：R246.5[医药卫生—针灸推拿学]