间苯三酚联合缩宫素对产程、宫颈水肿、母婴结局的影响研究  

Researches on the Effects of Phloroglucinol Combined with Oxytocin on the Outcomes of Labor,Cervical Edema and Maternal and Infant Outcomes

作　　者：李淑[1] Li Shu(Obstetric Department of People′s Hospital of Baise,Baise,Guangxi 533000,China)

机构地区：[1]百色市人民医院产科,广西百色533000

出　　处：《四川医学》2018年第10期1177-1180,共4页Sichuan Medical Journal

摘　　要：目的观察间苯三酚联合缩宫素对产程、宫颈水肿、母婴结局的影响。方法回顾性分析2016年2月至2017年8月在我院足月分娩的产妇的临床资料,根据其催产药物的不同分为对照组和观察组,对照组给予缩宫素静滴,观察组给予间苯三酚联合缩宫素。观察两组产妇产程、母婴结局和新生儿一般状况的差异。结果观察组产妇的第一产程、第二产程和第三产程均较对照组短(t=21.680、22.231、17.724,P<0.001);观察组产妇宫颈水肿、宫颈裂伤、感染发生率低于对照组(X^2=3.914,P=0.048);两组新生儿吸入性肺炎、颅内出血发生率无明显差别(X^2=0.346,P=0.556),两组新生儿出生后1min和5min的Apgar评分无明显差别(t=-0.317、-1.088,P=0.376、0.140);两组新生儿PH、PaCO_2、PO_2、SPO_2等血气指标无明显差别(t=0.735、-0.027、0.022、-0.032、-0.651,P=0.232、0.489、0.491、0.487、0.258)。结论间苯三酚联合缩宫素可明显缩短产程,降低产妇宫颈水肿等并发症发生率,且对新生儿并发症发生率和出生后的一般情况无明显影响,具有良好的临床应用价值。Objective To observe the effects of the combination of phloroglucinol and oxytocin on the duration of labor,cervical edema and maternal and infant outcomes.Methods The clinical data of women who gave birth in full term from February 2016 to August 2017 in our hospital were retrospectively analyzed.They were divided into the control group and the observation group according to the different oxytocin drugs.The control group was given pituitrin and the observation group received phloroglucinol combined with oxytocin.The differences of maternal delivery,maternal and infant outcomes and neonatal general status between the two groups were observed.Results The first,second and third birth stages of the observation group were shorter than those of the control group(t=21.680、22.231、17.724,P<0.001).The incidence of cervical edema,cervical laceration and infection in the observation group were lower than that in the control group(x^2=3.914,P=0.048).There was no significant difference in the incidence of aspiration pneumonia and intracranial hemorrhage between the two groups(x^2=0.346,P=0.556),and Apgar score was not significantly different between the two groups at 1min and 5min after birth(t=-0.317、-1.088,P=0.376、0.140).There was no significant difference in blood gas indexes such as PH,PaCO2,PO2,SPO2 and so on(t=0.735、-0.027、0.022、-0.032、-0.651,P=0.232、0.489、0.491、0.487、0.258)between the two groups.Conclusion The combination of phloroglucinol with oxytocin can significantly shorten the delivery process,reduce the incidence of complications such as maternal cervical edema,and have no significant impact on the incidence of neonatal complications and the general situation after birth,which has good clinical application value.

关 键 词：缩宫素 间苯三酚 宫颈水肿 产程 

分 类 号：R714.3[医药卫生—妇产科学]