肾区经穴敷熨对处于肾衰竭期的多囊肾患者的干预效果研究  

Effect Study of Renal Region Acupoint Compressing Therapy in the Treatment of Patients with Polycystic Kidney in Stage of Renal Failure

作　　者：王春寒 石伟 张茜英 贺艳光 刁平 杨启超 Wang Chunhan;Shi Wei;Zhang Qianying(The Eighth Nephrology Department of Shi Jiazhuang Nephrology Hospital,Shi Jiazhuang,Hebei 050061,China)

机构地区：[1]石家庄肾病医院肾八科,河北石家庄050061

出　　处：《四川医学》2018年第10期1181-1185,共5页Sichuan Medical Journal

基　　金：石家庄市科学技术研究与发展指导计划(编号:161460513)

摘　　要：目的探讨肾区经穴敷熨对处于肾衰竭期的常染色体显性遗传多囊肾(ADPKD)患者的治疗效果。方法选择2012年1月至2016年10月本院肾内科进行ADPKD治疗的处于肾衰竭期的400例患者,患者按照治疗的方法分为两个组,对照组和观察组,每个组完成治疗过程的患者数据均为200例。对照组患者施行常规对症治疗,观察组患者在对症治疗的基础上,进行中医肾区经穴敷熨的治疗,对效果进行分析和评价。结果对照组与观察组患者在T1(治疗之前),T2(治疗后1个月),T3(治疗后3个月),T4(治疗后6个月)四个时间点的血肌酐,尿素氮,尿酸,肾小球滤过率均出现变化,其中血肌酐为对照组患者从(513.26±14.15)μmol/L升高到(519.11±15.21)μmol/L,观察组患者从(514.95±13.32)μmol/L降低到(402.31±14.13)μmol/L;尿素氮为对照组患者从(8.47±2.01) mmol/L升高到(9.26±2.17) mmol/L,观察组患者从(8.57±2.37) mmol/L降低到(6.31±1.25) mmol/L;尿酸为对照组患者从(356.48±34.69)μmol/L升高到(391.22±42.41)μmol/L,观察组患者从(357.88±31.49)μmol/L降低到(294.42±31.37)μmol/L;内生肌酐清除率为对照组患者从(20.13±4.32) m L/min降低到(16.87±4.55) m L/min,观察组患者从(20.13±3.56) m L/min升高到(35.47±5.12) m L/min;采用重复测量数据的方差分析,结果显示:(1)在所有的项目中不同时间点间的数据差异有统计学意义(F=10.312,18.691,12.897,13.689,P<0.05);(2)对照组与观察组的数据差异有统计学意义(F=15.571,25.347,20.563,19.634,P<0.05),肾小球滤过率一项为观察组数据高于对照组,其余均为观察组数据低于对照组;(3)对照组与观察组的处理因素与时间具有交互作用(F=13.689,22.645,18.547,19.997,P<0.05),两组的治疗效果数据差异具有统计学意义(z=4.232,P<0.05),观察组的治疗效果显著优于对照组。结论利用中医肾区经穴敷熨的方法与常规对症治疗的方法对进入肾衰竭期的常染色体显性遗传多囊肾患者�Objective To investigate effect of renal region acupoint compressing therapy in the treatment of patients with autosomal dominant polycystic kidney disease(ADPKD)in stage of renal failure.Methods 400 cases of ADPKD patents in stage of renal failure treated in nephrology department of our hospital from January 2012 to October 2016 were included and divided into control group and observation group according to therapies,there being 200 cases in each group who finished the therapeutic process.Patients in the control group received conventional symptomatic treatment,while patients in the observation group received renal region acupoint compressing therapy on the basis of symptomatic treatment.The therapeutic effects of the two groups were analyzed and evaluated.Results Serum creatinine,urea nitrogen,uric acid and glomerular filtration rate of patients in both groups changed at time points of T1(before treatment),T2(1 month after treatment),T3(3 months after treatment)and T4(6 months after treatment).Serum creatinine of control group raised from(513.26±14.15)μmol/L to(519.11±15.21)μmol/L,while that of observation group decreased from(514.95±13.32)μmol/L to(402.31±14.13)μmol/L.Urea nitrogen of control group raised from(8.47±2.01)mmol/L to(9.26±2.17)mmol/L,while that of observation group decreased from(8.57±2.37)mmol/L to(6.31±1.25)mmol/L.Uric acid of control group raised from(356.48±34.69)μmol/L to(391.22±42.41)μmol/L,while that of observation group decreased from(357.88±31.49)μmol/L to(294.42±31.37)μmol/L.Endogenous creatinine clearance rate of control group decreased from(20.13±4.32)mL/min to(16.87±4.55)mL/min,while that of observation group raised from(20.13±3.56)mL/min to(35.47±5.12)mL/min.Repeated measurement data analysis of variance showed:①the differences of data among different time points in all items were statistically significant(F=10.312,18.691,12.897,13.689,P<0.05).②the difference between the control group and the observation group was statistically significant(F=15.571,25.347,

关 键 词：敷熨 多囊肾 中医 

分 类 号：R181.3[医药卫生—流行病学]