Leptomeningeal metastases originated from esophagogastric junction/gastric cancer:A brief report of two cases  

作　　者：Panteleimon Kountourakis Demetris Papamichael Haris Haralambous Michael Michael Georgios Nakos Sylvia Lazaridou Eleni Fotiou Vassilios Vassiliou Demetrios Andreopoulos 

机构地区：[1]Department of Medical Oncology,BOC Oncology Centre [2]Department of Radiology,BOC Oncology Centre [3]Department of Cytology,General Hospital of Nicosia [4]Department of Pathology,General Hospital of Nicosia [5]Department of Radiation Oncology,BOC Oncology Centre

出　　处：《World Journal of Gastrointestinal Oncology》2018年第1期56-61,共6页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Leptomeningeal carcinomatosis is a very rare manifestation in patients diagnosed with esophagogastric junction and gastric cancer. Its prognosis is ominous and therapy outcomes are disappointing. Herein, we present two patients; one initially diagnosed with gastric cancer and leptomeningeal carcinomatosis but no other evidence of metastatic disease and the other one initially diagnosed with esophagogastric junction cancer, who recurred solitary with leptomeningeal seedings several years after the initial diagnosis and treatment. Furthermore, a thorough and short review of the literature is carried out.Leptomeningeal carcinomatosis is a very rare manifestation in patients diagnosed with esophagogastric junction and gastric cancer. Its prognosis is ominous and therapy outcomes are disappointing. Herein, we present two patients; one initially diagnosed with gastric cancer and leptomeningeal carcinomatosis but no other evidence of metastatic disease and the other one initially diagnosed with esophagogastric junction cancer, who recurred solitary with leptomeningeal seedings several years after the initial diagnosis and treatment. Furthermore, a thorough and short review of the literature is carried out.

关 键 词：Esophagogastric JUNCTION CANCER GASTRIC CANCER LEPTOMENINGEAL CARCINOMATOSIS Prognosis Investigation Therapy 

分 类 号：R[医药卫生]