线粒体与胚胎质量相关性研究进展  

Advance in Correlation Between Mitochondria and Embryo Quality

作　　者：徐梓萌 马盼盼 栾维民[1] 马馨[1] XU Zi-meng;MA Pan-pan;LUAN Wei-min;MA Xin(College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,130118,China)

机构地区：[1]吉林农业大学动物科学技术学院,吉林长春130118

出　　处：《动物医学进展》2018年第11期102-106,共5页Progress In Veterinary Medicine

基　　金：吉林省自然科学基金项目(20170101018JC);国家自然科学基金青年基金项目(31302047)

摘　　要：线粒体是真核细胞能量工厂,通过呼吸作用为细胞供能,且具有调节胞内离子稳态、控制细胞分裂分化及凋亡、参与细胞信息传递等多种重要功能。早期胚胎中的线粒体被认为完全来自卵母细胞,在胚胎发育中起着至关重要的作用。线粒体的功能、数量、分布及线粒体DNA(mitochondrial DNA,mtDNA)的表达等与胚胎的附植、发育、代谢、凋亡等密切相关。论文就线粒体与胚胎质量间的相关性进行了综述。Mitochondria are the“energy factory”of the eukaryotic cells,generate energy via the process of respiration and have various other critical cellular functions,such as regulating intracellular homeostasis,controlling cell division,differentiation and apoptosis,and participating in cell information transmission.Mitochondria in early embryos are thought to be exclusively derived from the oocyte,and play a crucial role in embryonic development.The function,quantity,distribution and the expression of mitochondrial DNA play an important role in the attachment,development,metabolism and apoptosis of embryos.This article reviewed some recent advances in correlation between mitochondria and embryo quality.

关 键 词：线粒体功能 线粒体分布 线粒体数量 MTDNA 胚胎质量 

分 类 号：S857.22[农业科学—临床兽医学]