Surveillance of Australian Hajj pilgrims for carriage of potentially pathogenic bacteria:Data from two pilot studies  

作　　者：Mohammad Irfan Azeem Mohamed Tashani Al-Mamoon Badahdah Leon Heron Kristen Pedersen Neisha Jeoffreys Jen Kok Elizabeth Haworth Dominic E Dwyer Grant Hill-Cawthorne Harunor Rashid Robert Booy 

机构地区：[1]National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases,Kids Research Institute,the Children’s Hospital at Westmead [2]the Discipline of Child and Adolescent Health,Sydney Medical School,the University of Sydney [3]Marie Bashir Institute for Infectious Diseases and Biosecurity,the University of Sydney [4]Department of Family and Community Medicine,Faculty of Medicine in Rabigh,King Abdulaziz Uni-versity [5]Centre for Infectious Diseases and Microbiology Laboratory Services,Institute of Clinical Pathology and Medical Research,Pathology West,Westmead Hospital [6]Menzies Research Institute Tasmania [7]School of Public Health,the University of Sydney [8]World Health Organization Collaborating Centre for Mass Gatherings and High Consequence/High Visibility Events,Flinders University

出　　处：《World Journal of Clinical Cases》2017年第3期102-111,共10页世界临床病例杂志

基　　金：supported by the National Health and Medical Research Council (NHMRC) Centre of Research Excellence (CRE) in Population Health Research titled "Immunisation in under Studied and Special Risk Populations: Closing the Gap in Knowledgethrough a multidisciplinary Approach"

摘　　要：AIM To estimate the pharyngeal carriage rate of Neisseria meningitidis(N. meningitidis), Streptococcus pneumoniae(S. pneumoniae) and Staphylococcus aureus(S. aureus) among Australian Hajj pilgrims.METHODS In 2014, surveillance was conducted in two phases among Australian Hajj pilgrims: The first phase during Hajj in Mina, and the second phase soon after returning home to Australia. Nasopharyngeal or oropharyngeal swabs were taken from participants then tested, firstly by nucleic acid testing, and also by standard culture.RESULTS Of 183 participants recruited in the first phase, 26(14.2%) tested positive for S. pneumoniae; 4 had received pneumococcal conjugate vaccine(PCV13). Only one tested positive for N. meningitidis(W). Of 93 2^(nd) phase samples cultured, 17(18.3%) grew S. aureus, all methicillin sensitive, 2(2.2%) grew N. meningitidis(on subculture; one serotype B, one negative), and 1(1%), from an unvaccinated pilgrim, grew S. pneumoniae.CONCLUSION Relatively high carriage of S. pneumoniae and little meningococcal carriage was found. This indicates the importance of a larger study for improved infection surveillance and possible vaccine evaluation.AIM To estimate the pharyngeal carriage rate of Neisseria meningitidis(N. meningitidis), Streptococcus pneumoniae(S. pneumoniae) and Staphylococcus aureus(S. aureus) among Australian Hajj pilgrims.METHODS In 2014, surveillance was conducted in two phases among Australian Hajj pilgrims: The first phase during Hajj in Mina, and the second phase soon after returning home to Australia. Nasopharyngeal or oropharyngeal swabs were taken from participants then tested, firstly by nucleic acid testing, and also by standard culture.RESULTS Of 183 participants recruited in the first phase, 26(14.2%) tested positive for S. pneumoniae; 4 had received pneumococcal conjugate vaccine(PCV13). Only one tested positive for N. meningitidis(W). Of 93 2^(nd) phase samples cultured, 17(18.3%) grew S. aureus, all methicillin sensitive, 2(2.2%) grew N. meningitidis(on subculture; one serotype B, one negative), and 1(1%), from an unvaccinated pilgrim, grew S. pneumoniae.CONCLUSION Relatively high carriage of S. pneumoniae and little meningococcal carriage was found. This indicates the importance of a larger study for improved infection surveillance and possible vaccine evaluation.

关 键 词：CARRIAGE Conjugate vaccine Staphylococcus aureus Neisseria MENINGITIDIS STREPTOCOCCUS PNEUMONIAE HAJJ 

分 类 号：R181.3[医药卫生—流行病学]