Aggressive restenosis after percutaneous intervention in two coronary loci in a patient with human immunodeficiency virus infection  

作　　者：Mohammad Alkhalil Christopher P Conlon Houman Ashrafian Robin P Choudhury 

机构地区：[1]Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital [2]Department of Infectious Diseases, Churchill Hospital [3]Department of Cardiology, John Radcliffe [4]Oxford Acute Vascular Imaging Centre (AVIC), Radcliffe Department of Medicine, University of Oxford,John Radcliffe Hospital

出　　处：《World Journal of Clinical Cases》2017年第2期40-45,共6页世界临床病例杂志

摘　　要：A 54-year-old black African woman, 22 years human immunodeficiency virus(HIV)-positive, presented with an acute coronary syndrome. She was taking two nucleoside reverse transcriptase inhibitors and two protease inhibitors. Viral load and CD4 count were stable. Angiography revealed a right coronary artery lesion, which was treated with everolimus eluting stent. She also underwent balloon angioplasty to the first diagonal. She re-presented on three different occasions and technically successful coronary intervention was performed. The patient has reported satisfactory compliance with dual anti platelet therapy throughout. She was successfully treated with surgical revascularisation. The patient did not experience any clinical recurrence on follow up. This case demonstrates exceptionally aggressive multifocal and recurrent instent restenosis in a patient treated for HIV infection, raising the possibility of an association with HIV infection or potentially components of retro viral therapy.A 54-year-old black African woman, 22 years human immunodeficiency virus(HIV)-positive, presented with an acute coronary syndrome. She was taking two nucleoside reverse transcriptase inhibitors and two protease inhibitors. Viral load and CD4 count were stable. Angiography revealed a right coronary artery lesion, which was treated with everolimus eluting stent. She also underwent balloon angioplasty to the first diagonal. She re-presented on three different occasions and technically successful coronary intervention was performed. The patient has reported satisfactory compliance with dual anti platelet therapy throughout. She was successfully treated with surgical revascularisation. The patient did not experience any clinical recurrence on follow up. This case demonstrates exceptionally aggressive multifocal and recurrent instent restenosis in a patient treated for HIV infection, raising the possibility of an association with HIV infection or potentially components of retro viral therapy.

关 键 词：CORONARY ARTERY disease RESTENOSIS Human IMMUNODEFICIENCY virus 

分 类 号：R543.3[医药卫生—心血管疾病] R512.91[医药卫生—内科学]