七氟醚吸入复合米库氯铵、芬太尼诱导加喉罩正压通气在小儿麻醉中的应用效果  

The application effects of sevoflurane inhalation combined with induction anesthesia of mivacurium chloride and fentanyl as well as laryngeal mask positive pressure ventilation in children anesthesia

作　　者：马龙 迟晓慧[1] 卫晓娜[1] 侯俊德[1] 王志刚[1] 陈永学[1] MA Long;CHI Xiaohui;WEI Xiaona(Department of Anesthesiology,Central Hospital of Handan City,Hebei,Handan 056008,China)

机构地区：[1]河北省邯郸市中心医院麻醉科,056008

出　　处：《河北医药》2018年第22期3473-3475,共3页Hebei Medical Journal

摘　　要：目的研究七氟醚吸入复合米库氯铵、芬太尼诱导加喉罩正压通气在小儿麻醉中的应用效果。方法择期手术的80例患儿均行七氟醚吸入复合米库氯铵、芬太尼诱导麻醉。随机分为研究组和对照组,每组40例。研究组使用喉罩进行正压通气;对照组行气管插管正压通气。比较2组患儿的插管应激反应、呼吸道并发症发生状况。结果研究组、呼吸道并发症发生率均低于对照组,差异有统计学意义(P <0. 05)。研究组T2、T3心率、平均动脉压明显小于对照组,差异有统计学意义(P <0. 05)。2组心率、血压均在T2时达到峰值,随后逐渐降低。结论在小儿麻醉中行七氟醚吸入复合米库氯铵、芬太尼诱导麻醉,加用喉罩进行正压通气可以减少给患儿机体带来的应激反应,预防呼吸道并发症的发生。Objective To investigate the application effects of sevoflurane inhalation combined with induction anesthesia of mivacurium chloride and fentanyl as well as laryngeal mask positive pressure ventilation in children anesthesia.Methods A total of 80 children patients who were ready to receive elective surgery in our hospital from Jan.2014 to Jan.2017 were treated by sevoflurane inhalation combined with induction anesthesia of mivacurium chloride and fentanyl,then these patients were randomly divided into research group(n=40)and control group(n=40).The patients in research group were treated by laryngeal mask positive pressure ventilation,however,thepatients in control group were treated by trachea cannula positive pressure ventilation.The intubation stress reaction and incidence of respiratory complications were observed and compared between the two groups.Results The incidence of respiratory complications in research group was significantly lower than that in control group(P<0.05),and the heart rate in T2,T3 and mean arterial pressure in research group were significantly lower than those in control group(P<0.05).Moreover the heart rate and blood pressure in both groups reached peak in T2,then which were gradually decreased.Conclusion The application of sevoflurane inhalation combined with induction anesthesia of mivacurium chloride and fentanyl as well as laryngeal mask positive pressure ventilation in children anesthesia can decrease the stress reaction of hildren and prevent the occurrence of respiratory complications.

关 键 词：七氟醚 米库氯铵 芬太尼 喉罩 正压通气 小儿麻醉 

分 类 号：R971.2[医药卫生—药品]