ESR、FSHβ和PRLR基因与清平猪×大白猪杂交后代繁殖性能的关系  

Relationship between ESR,FSH,and PRLRgenes and reproductive performance in Qingping×Landrace hybrid population

作　　者：熊琪[1] 陈文娟 彭刚[2] 彭健[2] 柴进[2] 陈明新[1] 蒋思文[2] XIONG Qi;CHEN Wenjuan;PENG Gang;PENG Jian;CHAI Jin;CHEN Mingxin;JIANG Siwen(Hubei Key Laboratory of Animal Embryo Engineering and Molecular Breeding,Institute of Animal Husbandry and Veterinary,Hubei Academy of Agricultural Sciences,Wuhan 430064,China;Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry/Key Laboratory of Agricultural Animal Genetics,Breeding&Reproduction of Ministry of Education/The Cooperative Innovation Center for Sustainable Pig Production,Huazhong Agricultural University,Wuhan 430070,China)

机构地区：[1]湖北省农业科学院畜牧兽医研究所/动物胚胎工程及分子育种湖北省重点实验室,武汉430064 [2]华中农业大学农业动物遗传育种与繁殖教育部重点实验室/农业部猪遗传育种重点开放实验室/生猪健康养殖协同创新中心,武汉430070

出　　处：《华中农业大学学报》2018年第6期66-74,共9页Journal of Huazhong Agricultural University

基　　金：国家重点研发计划项目(2017YFD0502000)

摘　　要：为了挖掘清平猪妊娠期短和产仔数多等优良繁殖性状的遗传背景,在清平猪与大白猪杂交后的F1代和F2代黑猪群体中进行了ESR、FSHβ和PRLR与该群体繁殖性能的关联性分析。结果显示:(1)FSHβ基因在F1和F2群体中的A等位基因与B等位基因的基因频率相近;ESR在F1和F2群体中的优势基因均为B等位基因;PRLR基因在F1群体中的优势基因为C等位基因,在F2群体中C等位基因与T等位基因的基因频率相近。(2)FSHβ不同基因型对F1群体的产活仔数和F2群体的总产仔数、初生体质量、断奶仔猪体质量和3周龄体质量等重要繁殖性状均有显著影响。(3)ESR不同基因型对F2群体妊娠期长短的影响表现为AB<AA<BB,ESR基因的AB型个体具有较短的妊娠期,但AA型比BB型个体的木乃伊数多0.46头。(4)PRLR不同基因型对F1群体的妊娠期有极显著影响,对总产仔数、断奶仔猪数和70日龄体质量有显著影响;对F2群体的弱仔数、初生体质量、断奶仔猪体质量和3周龄体质量有显著影响。结果表明,清平猪杂交后代的选育过程中可以淘汰部分FSHβ基因AA型个体,应该提高有利基因B等位基因在群体中的频率;ESR基因的AB型有利于缩短妊娠期,可淘汰AA型个体;PRLR基因中T等位基因是繁殖性状的有利基因,但可能与弱仔性状正相关,须慎重选择。In order to explore the genetic background of short gestation period and high litter size of Qingping pigs,correlation analysis between ESR,FSHβand PRLR genes and the reproductive performance in F1 population and F2 black pigs of Qingping pigs×Landrace hybrid was carried out.The results showed that:(1)The gene frequency of A and B allele of FSHβwas similar in both F1 and F2 populations,while the predominant allele of ESR in both populations were B allele.The predominant allele of PRLR in F1 populations was C allele,and gene frequency of C and T allele in F2 population was similar.(2)Different genotypes of FSHβhad significant effects on the number of live piglets in F1 population,and on the total number of litters,birth weight,weaned piglet,and weight at 3 weeks of age in F2 population(P<0.05).(3)Effects of different ESR genotypes on gestation period in F2 were in the order of AB<AA<BB.The AB type of ESR had shorter gestation period,but AA genotype had more mummy pigs(0.46)than that of BB genotype.(4)Different PRLR genotypes had significant influence on gestation period(P<0.01),total number of litters,number of piglets weaned,and weight at 70 days of age(P<0.05)in F1 population,and had significant influence on the number of weak litters,birth weight,weight of weaned piglets,and weight at 3 weeks of age in F2 population(P<0.05).The above result indicated that during selection of Qingping pigs,AA type individuals of FSHβcould be eliminated,and frequency of B allele should be increased.The AB type of ESR gene could shorten the gestation period and the AA type individuals could be eliminated.The T allele of PRLR gene is favorable for reproductive traits,but it may be positively correlated with traits of weak litters,therefore this choice strategy demands careful consideration.

关 键 词：清平猪 候选基因 繁殖性状 关联性分析 

分 类 号：S828.2[农业科学—畜牧学]