Surgical management of osteonecrosis of the femoral head in patients with sickle cell disease  

作　　者：Atul F Kamath Michael H McGraw Craig L Israelite 

机构地区：[1]Department of Orthopedic Surgery,the Center for Hip Preservation,Penn Medicine,University of Pennsylvania

出　　处：《World Journal of Orthopedics》2015年第10期776-782,共7页世界骨科杂志（英文版）

摘　　要：Sickle cell disease is a known risk factor for osteonecrosis of the hip.Necrosis within the femoral head may cause severe pain,functional limitations,and compromise quality of life in this patient population.Early stages of avascular necrosis of the hip may be managed surgically with core decompression with or without autologous bone grafting.Total hip arthroplasty is the mainstay of treatment of advanced stages of the disease in patients who have intractable pain and are medically fit to undergo the procedure.The management of hip pathology in sickle cell disease presents numerous medical and surgical challenges,and the careful perioperative management of patients is mandatory.Although there is an increased risk of medical and surgical complications in patients with sickle cell disease,total hip arthroplasty can provide substantial relief of pain and improvement of function in the appropriately selected patient.Sickle cell disease is a known risk factor for osteonecrosis of the hip.Necrosis within the femoral head may cause severe pain,functional limitations,and compromise quality of life in this patient population.Early stages of avascular necrosis of the hip may be managed surgically with core decompression with or without autologous bone grafting.Total hip arthroplasty is the mainstay of treatment of advanced stages of the disease in patients who have intractable pain and are medically fit to undergo the procedure.The management of hip pathology in sickle cell disease presents numerous medical and surgical challenges,and the careful perioperative management of patients is mandatory.Although there is an increased risk of medical and surgical complications in patients with sickle cell disease,total hip arthroplasty can provide substantial relief of pain and improvement of function in the appropriately selected patient.

关 键 词：SICKLE cell disease Total HIP arthroplasty Core DECOMPRESSION ORTHOPEDIC OSTEONECROSIS AVASCULAR necrosis HIP 

分 类 号：R687.3[医药卫生—骨科学]