不同重建层厚对定量CT椎体骨密度测量值的影响  

Effect of different reconstruction slice thickness on vertebral bone mineral density using quantitative CT

作　　者：王勇朋[1] 阳琰[2] 何生生 钱堃[1] 程晓光[3] WANG Yong-peng;YANG Yan;HE Sheng-sheng(Imaging Department,the Affiliated Hospital of Zunyi Medical College,Guizhou 563003,China)

机构地区：[1]遵义医学院附属医院影像科,贵州563000 [2]遵义医学院附属医院内分泌科,贵州563000 [3]北京积水潭医院放射科,北京100035

出　　处：《放射学实践》2018年第11期1191-1193,共3页Radiologic Practice

基　　金：黔科合LH字(2017)7116号

摘　　要：目的:评估不同重建层厚对定量CT(QCT)椎体骨密度测量值的影响。方法:欧洲腰椎体模(ESP)作为标准,采用腰椎CT(250mA)和低剂量CT(80mA)两组扫描条件,以容积扫描方式对ESP重复扫描10次,分别以0.625mm、1.25mm、2.5mm重建层厚图像完成QCT椎体骨密度测量,分析不同重建层厚间椎体骨密度测量值准确度误差的差异。回顾性分析90例腰椎(250mA)骨密度测量者的原始图像,分别以0.625mm、1.25mm、2.5mm重建层厚完成QCT椎体骨密度测量,分析不同重建层厚间L1和L2椎体骨密度平均值的差异。结果:250mA和80mA两组中,ESP的L1、L2、L3椎体骨密度测量值准确度误差在不同重建层厚间差异均无统计学意义(P>0.05)。两组L1-3椎体平均骨密度测量值准确度误差均以1.25mm重建层厚时最小,250mA和80mA两组间1.25mm重建层厚ESP的L1、L2、L3椎体骨密度测量值准确度误差差异均无统计学意义(P>0.05)。90例患者不同重建层厚间L1和L2骨密度均值差异无统计学意义(P>0.05)。结论:不同重建层厚对QCT椎体骨密度测量值的影响无明显差异,1.25mm重建层厚骨密度测量值最接近真实值。Objective:The purpose of this study was to evaluate the effect of different reconstruction slice thickness on vertebral bone mineral density(BMD)using quantitative computed tomography(QCT).Methods:The standard European Spine Phantom(ESP)was respectively scanned for 10 times with routine lumbar(250mA)and low-dose(80mA)CT scanning protocols.The"standard L 1,L 2,L 3"vertebral BMD of ESP was measured by QCT on reconstruction images with different thickness,0.625mm,1.25mm,and 2.5mm.The accuracy error of vertebral BMD measurements with different thickness was calculated and compared.The BMD of L 1 and L 2 of a group of 90 cases from the database of BMD were measured by QCT respectively on reconstruction images with different thickness of 0.625mm,1.25mm,and 2.5mm,and the mean values of BMD of L 1 and L 2 with different thickness were compared.Results:There were no statistical differences in the accuracy error of BMD measurements of"ESP standard L 1,L 2,L 3"among different slice thickness in both routine and low dose groups(P>0.05).The mean accuracy error of BMD measurements of"L 1-3"with 1.25mm thickness was the lowest in both groups compared to other thickness.Moreover,no statistical differences was found in the accuracy error of"L 1,L 2,L 3"BMD with 1.25mm between the two groups(P>0.05).No statistical differences were found in the mean BMD of L 1 and L 2 with different reconstruction slice thickness(P>0.05)among 90 patients.Conclusion:Different reconstruction slice thickness has little effect on the vertebral BMD using QCT.The vertebral BMD with 1.25mm reconstruction thickness is the closest to the true value.

关 键 词：骨密度 骨质疏松 体层摄影术 X线计算机 图像处理 计算机辅助 

分 类 号：R814.42[医药卫生—影像医学与核医学] R336[医药卫生—放射医学]