低剂量胸部CT与QCT椎体骨密度测量一站式扫描可行性研究  

Low-dose chest CT and QCT "one-stop-shop" scan technology:a feasibility study

作　　者：王勇朋[1] 阳琰[2] 何生生 钱堃[1] 程晓光[3] WANG Yong-peng;YANG Yan;HE Sheng-sheng(Imaging Department,the Affiliated Hospital of Zunyi Medical College,Guizhou 563003,China)

机构地区：[1]遵义医学院附属医院影像科,贵州563000 [2]遵义医学院附属医院内分泌科,贵州563000 [3]北京积水潭医院放射科,北京100035

出　　处：《放射学实践》2018年第11期1194-1197,共4页Radiologic Practice

基　　金：黔科合LH字(2017)7116号

摘　　要：目的:探讨低剂量胸部CT与定量CT(QCT)骨密度测量一站式扫描的可行性。方法:腰椎CT(250mA)和低剂量胸部CT(80mA)两组扫描参数对欧洲脊柱体模(ESP)重复扫描10次,QCT测量ESP椎体骨密度、计算准确度误差并进行统计学分析。搜集既行低剂量胸部CT、又因其他原因行腰椎CT的40例患者,两次扫描间隔不超过1个月,QCT测量T_(12)~L_2椎体骨密度并分析结果。一组360例无症状体检者T_(12)~L_2椎体骨密度资料,分析T_(12)/L_1椎体骨密度均值与L_1/L_2椎体骨密度均值间相关性、并比较筛查法(依据T_(12)/L_1椎体骨密度均值)与推荐法(依据T_(12)/L_1椎体骨密度均值)评估骨密度诊断结果的一致性。结果:250mA和80mA两组间ESP"L_1、L_2、L_3"椎体骨密度准确度误差及40例患者T_(12)、L_1、L_2椎体骨密度差异均无统计学意义(P>0.05)。360例无症状体检者T_(12)/L_1与L_1/L_2椎体骨密度均值分别为157.104±33.480、153.352±33.299,二者具有明显相关性(r=0.988,P<0.05)。筛查法与推荐法评估骨密度诊断结果一致性好(Kappa=0.747,P<0.05)。结论:低剂量胸部CT与QCT一站式扫描,能同时满足肺筛查和评估骨密度需求,并且能降低辐射剂量、节约医疗成本及患者检查时间。Objective:To investigate the feasibility of"one-stop-shop"low-dose chest CT for lung screening and quantitative computed tomography(QCT)for bone mineral density(BMD)measurements.Methods:The European Spine Phantom(ESP)and 40 patients underwent routine lumbar CT scan(250mA)and low-dose chest CT scan(80mA).BMD was measured by QCT.The difference of diagnosis between screening method and classical method was compared in a total of 360 healthy persons from database of BMD.Results:There were no statistical differences between 250mA and 80mA in the accuracy errors of"L 1,L 2,L 3",and nor in BMD from T 12 to L 2(P>0.05).There was significant correlation(r=0.988,P<0.05)in mean BMD between T 12/L 1(157.104±33.480)and L 1/L 2(153.352±33.299).The diagnostic agreement between screening method and classical method in evaluating BMD was good(Kappa=0.747,P<0.05).Conclusion:Low-dose chest CT and QCT"one-stop-shop"scan can successfully obtain lung screening and assessment of BMD.Moreover,it can reduce the radiation dose,and save the medical cost and the patient's examination time.

关 键 词：骨密度 体层摄影术 X线计算机 辐射剂量 

分 类 号：R814.42[医药卫生—影像医学与核医学] R336[医药卫生—放射医学]