Osteonecrosis of the femoral head: An update in year 2012  

作　　者：Anjan P Kaushik Anusuya Das Quanjun Cui 

机构地区：[1]Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22903, United States [2]Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22903, United States

出　　处：《World Journal of Orthopedics》2012年第5期49-57,共9页世界骨科杂志（英文版）

摘　　要：Osteonecrosis is a phenomenon involving disruption to the vascular supply to the femoral head, resulting in articular surface collapse and eventual osteoarthritis. Although alcoholism, steroid use, and hip trauma remain the most common causes, several other etiologies for osteonecrosis have been identified. Basic science research utilizing animal models and stem cell applications continue to further elucidate the pathophysiology of osteonecrosis and promise novel treatment options in the future. Clinical studies evaluating modern joint-sparing procedures have demonstrated significant improvements in outcomes, but hip arthroplasty is still the most common procedure performed in these affected younger adults. Further advances in joint-preserving procedures are required and will be widely studied in the coming decade.Osteonecrosis is a phenomenon involving disruption to the vascular supply to the femoral head, resulting in articular surface collapse and eventual osteoarthritis. Although alcoholism, steroid use, and hip trauma remain the most common causes, several other etiologies for osteonecrosis have been identified. Basic science research utilizing animal models and stem cell applications continue to further elucidate the pathophysiology of osteonecrosis and promise novel treatment options in the future. Clinical studies evaluating modern joint-sparing procedures have demonstrated significant improvements in outcomes, but hip arthroplasty is still the most common procedure performed in these affected younger adults. Further advances in joint-preserving procedures are required and will be widely studied in the coming decade.

关 键 词：OSTEONECROSIS AVASCULAR necrosis FEMORAL head Total HIP ARTHROPLASTY Core DECOMPRESSION HIP 

分 类 号：R681.8[医药卫生—骨科学]