抑制紫色素杆菌12472群感效应放线菌的筛选  

Screening of Quorum Sensing Inhibitory from Actinomycete Strains against Chromobacterium violaceum

作　　者：穆永其 曾红[1] 陈伟[1,2] MU Yongqi;ZENG Hong;CHEN Wei(Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production&Construction Corps,College of Life Sciences,Tarim University,Alar Xinjiang 843300,China;Key Laboratory of Tarim Husbandry Science and Technology,Xinjiang Production&Construction Group,College of Animal Science,Tarim University,Alar Xinjiang 843300,China)

机构地区：[1]塔里木大学生命科学学院,新疆兵团塔里木盆地生物资源保护利用重点实验室,新疆阿拉尔843300 [2]塔里木大学动物科学学院,新疆兵团塔里木畜牧科技重点实验室,新疆阿拉尔843300

出　　处：《西北农业学报》2018年第10期1537-1540,共4页Acta Agriculturae Boreali-occidentalis Sinica

基　　金：国家自然科学基金(31260026);教育部新世纪优秀人才支持计划(NCET-11-10171)。

摘　　要：从新疆丰富的放线菌资源中,筛选能产生抑制紫色素杆菌群感效应活性物质的放线菌。采用微量板半定量法检测放线菌发酵液抑制Chromobacterium violaceum ATCC 12472群感效应的能力。筛选出活性稳定、能抑制紫色素杆菌12472群感效应的放线菌5株,分别为TRM10325、10303′、20813、10311、11402。To screen actinomycetes that can produce active substances and inhibit violacein production of Chromobacterium violaceum ATCC 12472 from the abundant actinomyces resources in Xinjiang,the microplate assay was used to detect atinomycetes strains.The results showed that there were five actinomycetes with stable activity and inhibition of violacein of C.violaceum 12472,which were TRM10325,10303′,20813,10311,and 11402.This study provides theoretical basis for the utilization of Xinjiang actinomycetes resources and for developping new drugs targeting to inhibit Quorum sensing.

关 键 词：紫色素杆菌 群感效应抑制剂 放线菌 筛选 

分 类 号：S476[农业科学—农业昆虫与害虫防治] Q93[农业科学—植物保护]