妊娠合并亚临床甲状腺功能减退症妊娠结局的临床观察  

Clinical observation of pregnancy outcome in pregnant women with subclinical hypothyroidism

作　　者：谭艳丽[1] 杨健红[1] 曾祥娥 姚毓筠 陈云贞 TAN Yanli;YANG Jianhong;ZENG Xiang’e;YAO Yuyun;CHEN Yunzhen(Obstetrics Department,Red Cross Hospital of Wuzhou City,Wuzhou 543002,China;Laboratory Department,Red Cross Hospital of Wuzhou City)

机构地区：[1]广西梧州市红十字会医院产科,广西梧州543002 [2]广西梧州市红十字会医院检验科

出　　处：《包头医学院学报》2018年第11期5-6,共2页Journal of Baotou Medical College

基　　金：广西梧州市科技计划项目(201402002)

摘　　要：目的:分析妊娠合并亚临床甲状腺功能减退症(亚甲减)与不良妊娠结局的相关性及左甲状腺素治疗对妊娠结局的影响。方法:选择孕早期甲减筛查为亚甲减孕妇80例分为治疗组及非治疗组,选取同期甲状腺功能正常孕妇作为对照组,比较三组的妊娠结局。结果:观察组流产、早产、妊娠期糖尿病、贫血、羊水过少等不良妊娠结局的发病率高于对照组(P <0. 05),治疗组流产、早产、妊娠期糖尿病、贫血、羊水过少等不良妊娠结局的发病率低于非治疗组(P <0. 05)。结论:妊娠合并亚甲减可增加不良妊娠结局的发生率,早期诊断、早期治疗能改善妊娠结局。Objective:To investigate the relationship between subclinical hypothyroidism(SCH)pregnant women and adverse pregnancy outcomes and the effect of levothyroxine on pregnancy outcomes.Methods:A total of 80 cases of SCH women in the first trimester of pregnancy were selected as the observation objects and divided into treatment group and non-treatment group.The control group was the pregnant women with normal thyroid function.The pregnancy outcomes of the three groups were compared.Results:The incidence of adverse pregnancy outcomes(abortion,premature delivery,gestational diabetes,anemia,and oligohydramnios)in the observation group was significantly higher than that in the control group(P<0.05).The incidence of adverse pregnancy outcomes in the treatment group was significantly lower than that in the non-treatment group(P<0.05).Conclusion:Pregnancy with SCH can increase the incidence of adverse pregnancy outcomes.Early diagnosis and treatment can effectively improve pregnancy outcomes.

关 键 词：亚临床甲状腺功能减退症 妊娠 左甲状腺素 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]