多边形电极线形离子阱质量分析器的结构与性能  

Structure and Performance of Polygonal Electrode Linear Ion Trap

作　　者：孙露露 许崇晟 徐福兴[2] 周振 丁传凡[2] SUN Lu-Lu;XU Chong-Sheng;XU Fu-Xing;ZHOU Zhen;DING Chuan-Fan(Institute of Mass Spectrometer and Atmospheric Environment,Jinan University,Guangzhou 510632,China;Department of Chemistry and Laser Chemistry Institute,Fudan University,Shanghai 200433 China)

机构地区：[1]暨南大学质谱仪器与大气环境研究所,广州510632 [2]复旦大学化学系激光化学研究所,上海200433

出　　处：《分析化学》2018年第12期1872-1877,共6页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(No.21773035)资助~~

摘　　要：多边形电极线形离子阱(PeLIT)可以产生四极场为主的电场分布,平衡了质量分辨和电极加工难度之间的关系,电极加工比较简单,同时又可以通过调节电极结构和电场分布实现较好的质量分辨水平。本研究分别从理论模拟仿真和质谱实验两个方面研究分析了PeLIT的结构和性能。仿真研究表明,不同结构的多边形电极线形离子阱具有不同的质量分析性能,负十二极场会显著降低其质量分析性能。实验结果表明,使用优化的多边形电极离子阱分析利血平离子(m/z=609),质量分辨率可达到2500以上。同时,多边形电极离子阱具有优良的质量选择激发以及串级质谱分析性能。The polygonal electrode linear ion trap(PeLIT)can produce quadrupolar electric field plus some higher order field,which balances the relationship between mass resolution and electrode manufactruing difficulties.The electrodes of PeLIT are relatively simple,but have a good mass resolving power.This study analyzed the structures and performances of PeLIT through theoretical simulation and experimental study.Simulations showed that the polygonal electrode linear ion traps with different structures had different mass analysis performances,and the negative decapole field reduced its performances significantly.The experimental results showed that the mass resolution of reserpine ions(m/z 609)was more than 2500 using a polygonal electrode ion trap.At the same time,mass selective excitation and tandem mass spectrometry experiments were also performed.

关 键 词：线形离子阱 多边形电极 理论仿真 质谱分析 质量分辨 

分 类 号：TH843[机械工程—仪器科学与技术]