真菌NBERC-170301中农药活性化合物的研究  

Study on the Pesticide Activity Compounds from Fungus NBERC-170301

作　　者：张亚妮[1] 方伟[1] 王开梅[1] 张志刚[1] 王燕[1] 万中义[1] 吴兆圆 ZHANG Ya-ni;FANG Wei;WANG Kai-mei;ZHANG Zhi-gang;WANG Yan;WAN Zhong-yi;WU Zhao-yuan(Hubei Biopesticide Engineering Research Center/The Branch Center of Biopesiticide,Hubei Agricultural Scientific and Technological Innovation Center,Wuhan 430064,China)

机构地区：[1]湖北省生物农药工程研究中心/湖北省农业科技创新中心生物农药分中心,武汉430064

出　　处：《湖北农业科学》2018年第22期60-63,共4页Hubei Agricultural Sciences

基　　金：国家重点研发项目(2017YFD0201205);湖北省技术创新专项重大项目(2016ABA103);湖北省农业科技创新中心创新团队项目(2016-620-000-001-039)

摘　　要：筛选到一株具有农药活性的真菌NBERC-170301,通过活性跟踪,确定出其中的活性组分。并经过大量发酵,提取分离得到4个化合物,经超高效液质联用(UPLC-MS)和NMR确定其中3个化合物分别为青霉酸、郝金青霉素和郝青霉素酮,活性测试结果表明,化合物4对小菜蛾具有较好的毒杀活性,但结构暂未确定。Fungus NBERC-170301 which had pesticide activity was found.By active tracking,the active fractions were detected,and 4 compounds were obtained(1-4).Compounds 1-3 were identified as penicillic acid(1),herqueichrysin(2)and herqueinone(3)by UPLC-MS and NMR.The results of biological activity showed that compound 4 had insecticidal activity against the Plutella xylostella L.,however,the structure of which was failed to be identified.

关 键 词：真菌NBERC-170301 农药活性 青霉酸 郝金青霉素 郝青霉素酮 

分 类 号：TQ450.1[化学工程—农药化工]