云南布朗山地区布朗族人群高尿酸血症及痛风的流行病学调查  

Epidemiological survey of hyperuricemia and gout in Bulang Ethnic population in the area of Bulang mountains in Yunnan Province

作　　者：晋松[1] 张娴 郑红梅[1] 李发有[1] 姚翔媚 JIN Song;ZHANG Xian;ZHENG Hongmei;LI Fayou;YAO Xiangmei(Department of Rheumatology,the First People's Hospital of Yunnan Province,Kunming 650032,China)

机构地区：[1]云南省第一人民医院风湿免疫科,昆明650032

出　　处：《实用医学杂志》2018年第22期3796-3800,共5页The Journal of Practical Medicine

摘　　要：目的了解云南省布朗山地区布朗族人群痛风及高尿酸血症(HUA)的流行病学特点。方法采用随机、整群分层抽样的方法,调查布朗山地区6个村寨的511例布朗族居民(男217例,女294例)痛风及HUA的患病情况。结果调查人群中HUA总患病率为34.38%(175/509),HUA标化后患病率为36.37%,其中男性为47.00%,女性为25.00%,痛风总患病率为9.39%(48/511),痛风标化后发病率为10.47%,其中男性为16.13%,女性为4.42%,男性HUA和痛风患病率均显著高于女性(P <0.05)。患者组与对照组相比在年龄、抽烟、饮酒、有家族痛风史、家族高尿酸史、合并慢性疾病、食用豆荚类食物方面差异均具有统计学意义(均P <0.05)。非条件Logistic回归分析结果显示,年龄、抽烟、饮酒、有家族痛风史、家族高尿酸史、合并慢性疾病是HUA的独立危险因素,食用豆荚类食物是HUA的保护因素。结论云南布朗山地区布朗族人群HUA和痛风患病率较高,应有针对性地改良布朗族生活及饮食中不良因素、改善当地医疗水平,可有助于防治当地HUA及痛风。Objective To research the epidemiologic characteristics ofhyperuricemia(HUA)and gout in Bulang Ethnic population in the area of Bulang mountains in Yunnan Province.Methods 511 Bulang people were enrolled from 6 villages in the area of Bulang mountains by stratified randomized cluster sampling survey,and the morbidity of HUA or gout were analyzed.Results The total prevalence of HUA in the survey population was 34.38%(175/509),and the standardized prevalence of HUA was 36.37%,of which the male was 47.00%and the female was 25.00%.The total prevalence of gout was 9.39%(48/511),and the standardized prevalence of gout was 10.47%,male was 16.13%and female was 4.42%.The prevalence of HUA and gout of male were significantly higher than that in female(P<0.05).Compared with the control group,the patient group had statistically significant differences in age,smoking,drinking,family history of gout,family history of hyperuricemia,chronic disease,and eating soybean meal(P<0.05).The multivariate regression analysis showed that the age,smoking,drinking,family history of gout,family history of hyperuricemia and chronic disease were independent risk factors for HUA,and eating soybean meal was protective factor for HUA.Conclusions The morbidities of HUA and gout are higher in the area of Bulang mountains than other areas.Targeting improvements of the bad factors in living and eating of Bulang people and the level of local health care,which can help prevent local HUA and gout.

关 键 词：布朗族 痛风 高尿酸血症 流行病学 危险因素 

分 类 号：R589.7[医药卫生—内分泌]