激光溶脂手术脉冲式制冷剂喷雾冷却数值研究  

Numerical study of multi-pulsed cryogen spray cooling for laser lipolysis

作　　者：辛慧[1] 陈斌[1] 周致富[1] 田加猛 XIN Hui;CHEN Bin;ZHOU Zhifu;TIAN Jiameng(State Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an 710049, Shaanxi, China)

机构地区：[1]西安交通大学动力工程多相流国家重点实验室,陕西西安710049

出　　处：《化工学报》2018年第12期4966-4971,5380,共7页CIESC Journal

基　　金：国家自然科学基金重大科研仪器研制项目(51727811)~~

摘　　要：无创激光溶脂发展潜力巨大,但水对近红外激光的吸收可能导致真皮热损伤。目前尚无有效的正常组织冷保护措施,制约了激光溶脂的发展。提出采用多脉冲喷雾冷却的方式对人体皮肤进行冷保护,建立皮肤组织多层均匀模型,结合Pennes生物传热方程数值模拟制冷剂R134a连续和脉冲式喷雾对皮肤深层组织的冷却效果。发现相同累计喷雾时间下多脉冲喷雾的冷却深度大于连续式喷雾,从冷却温度和冷却深度上更适合于激光溶脂的皮肤冷却。在单次喷雾时间10 ms、间隔时间2500 ms、喷雾次数10次、占空比0.004的条件下,冷却深度达到5000μm,1 mm深度的皮肤组织喷雾中心温度最低能达到11℃,可以有效满足激光溶脂对皮肤冷却深度的要求。Noninvasive or minimally invasive laser lipolysis has great potential to reduce obesity,but the absorption of near infrared laser by water may cause thermal damage of dermis.At present,there is no effective cooling method to protect normal skin tissue from thermal injury,which restricts the development of laser lipolysis.A novel multipulsed cryogen spray cooling for laser lipolysis was proposed to protect epidermis and dermis.Numerical simulation based on multi-layer uniform skin tissue model and Pennes biological heat transfer equation was conducted to investigate the cooling effect of continuous and multi-pulsed R134a cryogen spray cooling.It was found that continuous spray cannot meet the requirement of laser lipolysis both in temperature and skin depth.Under the same accumulative spray time,the cooling depth of multi-pulsed spray is greater than that of continuous spray.The lowest temperature at1mm below skin surface after multi-pulsed cryogen spray can reach to11℃with pulse width of10ms,interval time of2500ms,spray times of10and duty cycle of0.004,and the simulation cooling depth achieves5000μm,which can satisfy the cooling depth requirement of laser lipolysis.

关 键 词：激光溶脂 R134A 多脉冲喷雾冷却 数值模拟 传热 生物医学工程 

分 类 号：TK124[动力工程及工程热物理—工程热物理]