基于关联规则和复杂系统熵聚类的国医大师熊继柏治疗脾胃病证用药规律研究  

A Study of Chinese Medicine Master Xiong Jibo's Medication Rule in Prescriptions for Spleen and Stomach Diseases Based on Association Rules and Entropy Clustering for Complex Systems

作　　者：黄亮[1] 余娜[1] 晏峻峰[1] HUANG Liang;YU Na;YAN Junfeng(Hunan University of Chinese Medicine, Changsha, Hunan 410208, China)

机构地区：[1]湖南中医药大学,湖南长沙410208

出　　处：《湖南中医药大学学报》2018年第12期1412-1415,共4页Journal of Hunan University of Chinese Medicine

基　　金：国家中医药管理局"国医大师熊继柏传承工作室建设项目"资助

摘　　要：目的研究熊继柏教授治疗脾胃病证的用药规律及组方规律。方法收集录入熊继柏教授治疗脾胃病证的医案处方数据,采用Apriori关联规则算法,改进的复杂系统熵聚类算法等无监督数据挖掘算法,确定处方中各种药物的使用频次以及药物之间的关联规则,分析熊继柏教授治疗脾胃病证的用药经验以及组方规律。结果对脾胃病证筛选出的29个医案,共71首处方、108味中药进行分析,使用频次较高的中药是甘草、陈皮、砂仁、茯苓、木香、法半夏、厚朴、枳实;使用频次较高的药对是"陈皮-甘草""砂仁-甘草""茯苓-甘草";挖掘出熊继柏教授治疗脾胃病的4个核心组合及1首新处方。结论熊继柏教授治疗脾胃病证多用醒脾开胃,行气化湿之药品。Objective To study Professor Xiong Jibo's medication and prescription rules for spleen and stomach diseases.Methods The medical records and prescription data of Professor Xiong Jibo in the treatment of spleen and stomach diseases were collected and enrolled in this study.Two unsupervised data mining algorithms,Apriori association rule algorithm and improved entropy clustering algorithm for complex systems,were used to determine the usage frequency of medicines and association rules between medicines in prescriptions.The medication experiences and prescription rules of Professor Xiong Jibo were analyzed in the treatment of spleen and stomach diseases.Results A total of29medical records,including71prescriptions and108traditional Chinese medicines,for spleen and stomach diseases were analyzed.The most frequently used medicines were Radix Glycyrrhizae,tangerine peel,Amomum villosum,Poria cocos,Saussurea costus,Rhizoma Pinelliae Praeparatum,Magnolia officinalis,and Fructus Aurantii Immaturus.The most frequently used medicine pairs were tangerine peel-Radix Glycyrrhizae,Amomum villosum-Radix Glycyrrhizae,and Poria cocos-Radix Glycyrrhizae.Four core combinations and one new prescription were identified in Professor Xiong Jibo's medical records for spleen and stomach diseases.Conclusion To treat spleen and stomach diseases,Professor Xiong Jibo often uses medicines that arouse the spleen,open the stomach,move Qi,and remove dampness.

关 键 词：脾胃病证 熊继柏 关联规则 复杂系统熵聚类 

分 类 号：R256.3[医药卫生—中医内科学]