兔单椎体压缩性骨折的应力-应变关系  

Stress-strain relations of single-level vertebrae compression fracture in rabbits

作　　者：李洲 韩世冰 张玉文 郭媛 张绪树 Li Zhou;Han Shibing;Zhang Yuwen;Guo Yuan;Zhang Xushu(College of Mechanics,Taiyuan University of Technology,Taiyuan 030024,Shanxi Province,China)

机构地区：[1]太原理工大学力学学院,山西省太原市030024

出　　处：《中国组织工程研究》2019年第4期538-544,共7页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金项目(11102126);课题名称:肘关节接触压力分布的实验和有限元仿真研究;项目负责人:郭媛;国家自然科学基金项目(11472185);课题名称:高处坠落时脊柱损伤机制研究;项目负责人:郭媛~~

摘　　要：背景:脊柱是人体的中轴,结构复杂且功能多样。脊柱损伤,不但对感觉、运动系统等产生影响,甚至可能造成终生残疾或危及生命。目的:通过单轴压缩破坏实验,分析兔椎体的生物力学特性及压缩载荷下的应力-应变关系,探讨兔龄、椎体类型等因素对椎体极限载荷、应力、应变等的影响,为临床上人脊柱压缩性骨折的预测和防护提供生物力学参考。方法:通过材料性能试验机进行椎体轴向和侧向压缩实验,在椎体腹侧中部粘贴应变计,记录试验机的载荷以及应变计的应变等数据;通过对兔脊柱进行CT扫描,获得椎体的横截面积。结果与结论:(1)兔龄对极限载荷的影响较显著,且随着兔龄增加,多数同名椎体可承受的极限载荷也相应增加;(2)脊柱生理弯曲转折位置的椎体易发生骨折或破坏;(3)此文的研究结果也可用于兔椎体压缩有限元分析的模型验证。BACKGROUND:Spine is the central axis of the body,and has complex structure and versatile functions.Spinal injury will not only affect the sensory and movement systems,but may even result in life-long disability or life-threatening injuries.OBJECTIVE:To analyze the stress-strain relations of the rabbit vertebrae obtained by uniaxial compression,and to explore the effects of rabbit age,body weight,and vertebral body type on the vertebral load,stress,and strain in order to provide biomechanical guidance to spinal compression fractures.METHODS:Axial and lateral compression experiments of the vertebral body were performed through a material properties tester,strain gauges were attached to the ventral middle part of the vertebral bodies,and the data such as the load of the tester and the strain were recorded.The sectional area of vertebrae was obtained by CT scanning for rabbit spine.RESULTS AND CONCLUSION:(1)The rabbit age had a significant effect on the ultimate load,and with age increasing,the ultimate load of most of vertebrae could bear was increased.(2)The vertebral body at the turning point of spine physiological bending was liable to fracture or damage.(3)Our results can be employed to validate the finite element analysis model of rabbit vertebral compression.

关 键 词：脊柱损伤 骨折 压缩性 生物力学 组织工程 兔脊柱 单椎体压缩性骨折 极限载荷 极限应变 骨折后应力-应变 国家自然科学基金 

分 类 号：R459.9[医药卫生—治疗学]