冠状动脉微循环功能评价方法的应用进展  

Progress of Evaluation to Coronary Microcirculation Function

作　　者：吴建涛[1] 刘峰[2] 魏青政 牛兆倬[1] WU Jian-tao;LIU Feng;WEI Qin-zheng;NIV Zhao-Zhuo(Department of Cardiovascular;Qingdao Municipal Hospital,Medical College of Qingdao University,Qingdao 266071,China;Department of Medical Imaging.Qingdao Municipal Hospital,Medical College of Qingdao University,Qingdao 266071,China;Department of E.N.T,Qingdao Municipal Hospital,Medical College of Qingdao University,Qingdao 266071,China)

机构地区：[1]青岛大学医学院附属青岛市立医院心脏病中心,青岛266071 [2]青岛大学医学院附属青岛市立医院医学影像科,青岛266071 [3]青岛大学医学院附属青岛市立医院医学检验科,青岛266071

出　　处：《微循环学杂志》2018年第4期75-80,共6页Chinese Journal of Microcirculation

基　　金：山东省青岛市科技局资助项目(2016-YY-039)

摘　　要：心脏疾病病理生理研究重心已由心外膜下冠状动脉病变逐步向冠状动脉微循环(CMV)功能改变转移,心脏X综合征、应激性心肌病及冠状动脉血运重建术后的无复流和慢血流现象等的CMV受到更重视。随着诊断设备技术的进步,CMV评价出现了一些新方法。目前主要有冠状动脉造影血流分级技术(TIMI血流分级)、心电图、冠脉血流储备分数(FFR)、超声技术(心肌声学造影、冠状动脉血流超声显像、瞬测血流量技术等)、PET、心脏磁共振显像(CMR)、冠状动脉微循环阻力指数(IMR)及细胞学等;未来评价CMV将呈现分子生物学、细胞学及影像学等多学科融合应用发展。Studies on pathophysiology of heart disease have shifted gradually from subpericardial coronary artery to smaller coronary microcirculation vascular function(CMV).CMV of cardiac X syndrome,stress cardiomyopathy,non-reflow and slow flow after coronary artery revascularization and microangiopathy of donor heart after heart transplantation,which urge people to pay more with the progress of science and technology in recent years,a new way of evaluating CMV appears.At present,the main evaluation methods of CMV commonly used are coronary angiography(TIMI),electrocardiogram(ECG),coronary flow fraction reserve(FFR),ultrasound(myocardial contrast echocardiography,coronary flow ultrasound imaging,transit time flow meters),PET,cardiac magnetic resonance(CMR),index of microcirculatory resist-ance(IMR),cytology and so on.The evaluation methods of CMV will be evolved into a combination of molecular biology,cytology,and imaging in the future.

关 键 词：冠脉微循环 声学造影 心肌磁共振显像 冠状动脉微循环阻力指数 

分 类 号：R540.4[医药卫生—心血管疾病] R816.2[医药卫生—内科学]