不合理多药联用导致Stevens-Johnson综合征1例  

One Case of Stevens-Johnson Syndrome Caused by Irrational Combination of Multiple Drugs

作　　者：丰航[1] 李茁[1] 张鹏[1] Feng Hang;Li Zhuo;Zhang Peng(Department of Pharmacy,Shaanxi Provincial People's Hospital,Xi′an,Shaanxi,China 710068)

机构地区：[1]陕西省人民医院药学部,陕西西安710068

出　　处：《中国药业》2018年第24期115-117,共3页China Pharmaceuticals

摘　　要：目的提醒临床应重视不适宜的药物联用所引起的药源性疾病,提高安全、合理用药意识。方法回顾性分析1例不适宜的多药联用致重症Stevens-Johnson综合征的临床资料,分析其基本信息、用药方案、诊疗过程、药源性疾病和治疗结果。结果患者罹患Stevens-Johnson综合征确为不良反应。结论不适宜的多药联用可致药源性疾病。Objective To remind clinicians to pay attention to drug-induced disease( DID) caused by unsuitable combined pharmacotherapy,and to improve awareness of safe and rational drug use. Methods The clinical data of a patient with severe Stevens-Johnson syndrome caused by unsuitable combined pharmacotherapy was retrospective analyzed,and the basic information,medication regimen,diagnosis and treatment process,DID and the result of treatment were analyzed. Results The patient’s Stevens-Johnson syndrome was indeed a adverse drug reaction. Conclusion The unsuitable combined pharmacotherapy could lead to DID.

关 键 词：合理用药 STEVENS-JOHNSON综合征 多药联用 头孢噻肟 清开灵注射液 激素冲击疗法 

分 类 号：R969.3[医药卫生—药理学] R986[医药卫生—药学]