羧化壳聚糖纤维止血机理研究  

The Hemostatic Mechanism of Carboxyl Chitosan Fibers

作　　者：梁凯利 周鼎 张灿 周应山 LIANG Kai-li;ZHOU Ding;ZHANG Can;ZHOU Ying-shan(College of Materials Science and Engineering,Wuhan Textile University,Wuhan 430073,China;State Key Laboratory of New Textile Materials and Advanced Processing Technologies,Wuhan Textile University,Wuhan 430073,China)

机构地区：[1]武汉纺织大学材料科学与工程学院,湖北武汉430073 [2]武汉纺织大学湖北省纺织新材料与先进加工技术省部共建国家重点实验室培育基地,湖北武汉430073

出　　处：《服饰导刊》2018年第6期48-52,共5页Fashion Guide

基　　金：湖北省教育厅科研项目(D20151605)

摘　　要：壳聚糖因其对红细胞的诱导聚集作用以及对血小板的活化作用而具有良好的止血效果。然而,因其剂型不同,其止血效果及止血机理不尽相同。本文对本实验室自制的羧化壳聚糖纤维的止血机理进行了探究,主要结果表明,羧化壳聚糖纤维主要通过超吸收血液中的水分促使红细胞、血小板的富集从而达到迅速止血的效果。该羧化壳聚糖纤维未来有望在急救止血领域中得到广泛应用。Chitosan exhibits a good hemostatic abi lity,due to its excellent characteristics including induction of red blood cell aggregation,acceleration of platelet adhesion and activation.However,different types of chitosan show different hemostatic effects and mechanisms.This study investigated the hemostatic mechanism of carboxyl chitosan fibers and showed that carboxyl chitosan fibers could accelerate red blood cell and platelet aggregation to stop blood loss by rapidly adsorbing water in blood owing to their highly hydrophilic fiber structure.The carboxyl chitosan fibers would be widely applied in first-aid hemostasis fields.

关 键 词：羧化壳聚糖 纤维 止血机理 

分 类 号：TQ342.87[化学工程—化纤工业]